Evidence map›Paper›PMID 34945119›Full record

ArticleJournal of clinical medicine2021

Blood Cultures for the Diagnosis of Infective Endocarditis: What Is the Benefit of Prolonged Incubation?

Vincent Fihman, Hélène Faury, Amina Moussafeur, Raphaelle Huguet, Adrien Galy, Sébastien Gallien, Pascal Lim, Raphaël Lepeule, Paul-Louis Woerther

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Prosthetic valve infective endocarditis caused byEuropean heart journal. Case reports · 2024
    Article
  2. Article
  3. Unresolved issues in the epidemiology and diagnosis of bacteremia: an opinion paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Vincent FihmanBacteriology and Infection Control Unit, Department of Prevention, Diagnosis, and Treatment of Infections, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.ORCID 0000-0001-9327-7524
Hélène FauryBacteriology and Infection Control Unit, Department of Prevention, Diagnosis, and Treatment of Infections, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Amina MoussafeurDepartment of Cardiovascular Medicine, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Raphaelle HuguetDepartment of Cardiovascular Medicine, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Adrien GalySOS Endocardites Unit, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Sébastien GallienSOS Endocardites Unit, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Pascal LimDepartment of Cardiovascular Medicine, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Raphaël LepeuleSOS Endocardites Unit, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.
Paul-Louis WoertherBacteriology and Infection Control Unit, Department of Prevention, Diagnosis, and Treatment of Infections, Henri-Mondor University Hospital, AP-HP, 94000 Creteil, France.ORCID 0000-0002-6957-9482
Assistance Publique – Hôpitaux de Paris · FRUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the need for prolonged incubation of blood culture bottles beyond five days for the diagnosis of infectious endocarditis (IE), we conducted a retrospective cohort study of 6109 sets of two blood culture bottles involving 1211 patients admitted to the Henri Mondor University Hospital for suspicion of IE between 1 January 2016 and 31 December 2019. Among the 322 patients with IE, 194 had positive blood cultures in our centre. Only one patient with a time-to-positivity blood culture of more than 120 h (5 days) was found. The main cause for the 22 patients with positive blood cultures after five days was contamination with

Indexed as

Cutibacterium acnesinfective endocarditisprolonged incubationtime-to-positivity blood culture

Identifiers

PMID34945119
PMCPMC8705825
OpenAlexW4200011529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.