Evidence map›Paper›PMID 34945118›Full record

ArticleJournal of clinical medicine2021

Fecal Microbiota Transplant in Severe and Non-Severe

Daniel Popa, Bogdan Neamtu, Manuela Mihalache, Adrian Boicean, Adela Banciu, Daniel Dumitru Banciu, Doru Florian Cornel Moga, Victoria Birlutiu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Advances in Fecal Microbiota Transplantation for Gut Dysbiosis-Related Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Le infezioni in medicina · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daniel PopaFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Bogdan NeamtuFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.ORCID 0000-0003-2573-621X
Manuela MihalacheFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Adrian BoiceanFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Adela BanciuDepartment of Bioengineering and Biotechnology, Faculty of Medical Engineering, Polytechnic University of Bucharest, 011061 Bucharest, Romania.
Daniel Dumitru BanciuDepartment of Bioengineering and Biotechnology, Faculty of Medical Engineering, Polytechnic University of Bucharest, 011061 Bucharest, Romania.
Doru Florian Cornel MogaFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Victoria BirlutiuFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Lucian Blaga University of Sibiu · ROUniversity of Bucharest · RO

Funding

Lucian Blaga University of Sibiu & Hasso Plattner Foundation LBUS-IRG-2021-07
6 · The paper itself

Abstract

backgroundFaecal microbiota transplant (FMT) is a highly effective therapy for recurrent

methodsWe conducted a retrospective study to analyze the clinical characteristics and the outcomes of 96 FMT patients with a prior 10 day course of antibiotic treatment in the medical records, of which 71 patients with recurrent CDI and 25 patients with a primary CDI.

resultsThe overall primary cure rate in our study was 88.5% and the primary cure rate for the severe forms was 85.7%. The data analysis revealed 5.25%, 15.15%, and 27.3% FMT recurrence rates for primary, secondary, and tertiary severe CDI. The risk of recurrence was significantly associated with FMT after the second and the third CDI severe episodes (

conclusionsThis study brings new data in supporting the FMT role in CDI treatment, including the primary severe CDI, however, further prospective and controlled studies on larger cohorts should be performed in this respect.

Indexed as

Clostridioides difficilefecal microbiota transplantprimary infectionrecurrence

Identifiers

PMID34945118
PMCPMC8707415
OpenAlexW4200037536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.