Evidence map›Paper›PMID 34945047›Full record

ArticleJournal of clinical medicine2021

Self-Collected Samples to Detect SARS-CoV-2: Direct Comparison of Saliva, Tongue Swab, Nasal Swab, Chewed Cotton Pads and Gargle Lavage.

Niko Kohmer, Lisa Eckermann, Boris Böddinghaus, Udo Götsch, Annemarie Berger, Eva Herrmann, Marhild Kortenbusch, Peter Tinnemann, Rene Gottschalk, Sebastian Hoehl and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Niko KohmerInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.
Lisa EckermannInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.
Boris BöddinghausHealth Protection Authority, City of Frankfurt, 60313 Frankfurt, Germany.
Udo GötschHealth Protection Authority, City of Frankfurt, 60313 Frankfurt, Germany.
Annemarie BergerInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.
Eva HerrmannInstitute of Biostatistics and Mathematical Modelling, Goethe University Frankfurt, 60596 Frankfurt, Germany.
Marhild KortenbuschInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.
Peter TinnemannHealth Protection Authority, City of Frankfurt, 60313 Frankfurt, Germany.
Rene GottschalkInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.ORCID 0000-0003-0422-6456
Sebastian HoehlInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.ORCID 0000-0002-5100-9385
Sandra CiesekInstitute for Medical Virology, University Hospital, Goethe University Frankfurt, 60596 Frankfurt, Germany.ORCID 0000-0002-1802-7565
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by RT-PCR is a vital public health tool in the pandemic. Self-collected samples are increasingly used as an alternative to nasopharyngeal swabs. Several studies suggested that they are sufficiently sensitive to be a useful alternative. However, there are limited data directly comparing several different types of self-collected materials to determine which material is preferable. A total of 102 predominantly symptomatic adults with a confirmed SARS-CoV-2 infection self-collected native saliva, a tongue swab, a mid-turbinate nasal swab, saliva obtained by chewing a cotton pad and gargle lavage, within 48 h of initial diagnosis. Sample collection was unsupervised. Both native saliva and gargling with tap water had high diagnostic sensitivity of 92.8% and 89.1%, respectively. Nasal swabs had a sensitivity of 85.1%, which was not significantly inferior to saliva (

Indexed as

COVID-19gargle lavagenasal swabPCRsalivaSARS-CoV-2self-collected samples

Identifiers

PMID34945047
PMCPMC8709431
OpenAlexW4200334584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.