Evidence map›Paper›PMID 34945043›Full record

ArticleJournal of clinical medicine2021

Metabolic Syndrome Severity Score, Comparable to Serum Creatinine, Could Predict the Occurrence of End-Stage Kidney Disease in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Pil Gyu Park, Jung Yoon Pyo, Sung Soo Ahn, Jason Jungsik Song, Yong-Beom Park, Ji Hye Huh, Sang-Won Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pil Gyu ParkDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-2788-6580
Jung Yoon PyoDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.
Sung Soo AhnDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-9002-9880
Jason Jungsik SongDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.
Yong-Beom ParkDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.
Ji Hye HuhDivision of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang 14068, Gyeonggi-do, Korea.
Sang-Won LeeDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-8038-3341
Yonsei University · KRHallym University Sacred Heart Hospital · KR

Funding

a faculty research grant of Yonsei University College of Medicine 6-2019-0184
6 · The paper itself

Abstract

This study investigated whether the metabolic syndrome (MetS) severity (MSSS) at diagnosis could predict poor outcomes during follow-up in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients with MetS. The equation for the MSSS at diagnosis used in this study was developed and validated in Korean adults aged 20-59 years. The medical records of 261 patients with AAV were retrospectively reviewed, and finally, 36 AAV patients with MetS aged 20-59 years fulfilling the inclusion criteria were included in this study. All-cause mortality, relapse, end-stage kidney disease (ESKD), cerebrovascular accident, and cardiovascular disease were assessed as the poor outcomes of AAV. Their median age was 51.2 years and 36.1% were male. The MSSS was significantly correlated with age and serum albumin but not AAV-specific indices. Among the five poor outcomes, only ESKD showed a relatively significant area under the curve (area 0.696) in receiver operating characteristic curve analysis. In the multivariable Cox hazards model analysis, both serum creatinine (HR 3.033) and MSSS (HR = 2.221) were significantly associated with ESKD occurrence. When the cut-off of the MSSS for ESKD was set at 1.72, ESKD occurred more frequently in patients with MSSS ≥ 1.72 than in those with MSSS < 1.72 (75.0% versus 14.3%,

Indexed as

antineutrophil cytoplasmic antibodyend-stage kidney diseasemetabolic syndromeseverity scorevasculitis

Identifiers

PMID34945043
PMCPMC8708376
OpenAlexW4200061538

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.