ReviewCancers2021
Radiation Therapy for Adenoid Cystic Carcinoma of the Head and Neck.
Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Clinical Features, Treatment, and Outcomes for Oropharyngeal Adenoid Cystic Carcinoma: A Systematic Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Pooled it
- Multimodal imaging features of nuclear protein in testis carcinoma of the submandibular gland: a case report.Journal of medical case reports · 2026Article
- Article
- Differential Diagnosis of Oral Salivary Gland Carcinoma and Squamous Cell Carcinoma Using Quantitative Dynamic Contrast-Enhanced MRI.Journal of clinical medicine · 2026Article
- Case Report: transcavernous sinus resection of parotid carcinoma with perineural invasion to Meckel's cave and cavernous sinus.Frontiers in oncology · 2026Article
- The Use of Proton Radiation in the Management of Adenoid Cystic Carcinoma.International journal of particle therapy · 2025Article
- Adenoid cystic carcinoma in an 86-year-old male patient: A rare case report.Radiology case reports · 2025Article
- Diagnostic values of diffusion-weighted imaging and dynamic contrast-enhanced MRI in the pathological grading of adenoid cystic carcinoma.BMC medical imaging · 2025Article
- Adenoid cystic carcinoma brain metastases treated with stereotactic radiosurgery: A single institution retrospective cohort study and comprehensive literature review.Neurosurgical review · 2025Review
- miR-429 suppresses progression and metastasis of salivary adenoid cystic carcinoma by targeting ZEB1.Journal of molecular histology · 2025Article
- Sympathetic axonogenesis promotes adenoid cystic carcinoma progression.The Journal of experimental medicine · 2025Article
- Current Insights on Salivary Gland Adenoid Cystic Carcinoma: Related Genes and Molecular Pathways.Genes · 2025Review
- Revealing the Enigma: A Deep Dive Into Submandibular Adenoid Cystic Carcinoma and Its Management.Cureus · 2024Article
- Feasibility of stereotactic radiotherapy with pembrolizumab in patients with deficient mismatch repair/microsatellite unstable metastatic colorectal cancer.ESMO gastrointestinal oncology · 2024Article
- Long-term treatment of metastatic adenoid cystic carcinoma with sequential brachytherapy and stereotactic body radiotherapy.Radiation oncology journal · 2024Article
- Adenoid cystic carcinoma: insights from molecular characterization and therapeutic advances.MedComm · 2024Review
- Article
- Cavernous sinus adenoid cystic carcinoma mimicking meningioma: a case study and literature analysis.Quantitative imaging in medicine and surgery · 2024Article
- Article
- A Review of the Molecular Landscape of Adenoid Cystic Carcinoma of the Lacrimal Gland.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenoid cystic carcinoma of the head and neck is an uncommon malignancy that can arise in the major or minor salivary glands. Perineural invasion (PNI) is an extremely frequent finding in cases of adenoid cystic carcinoma (ACC) that can be associated with significant patient morbidity and poor prognosis. By contrast, ACC rarely demonstrates lymphovascular space invasion thereby making PNI the major avenue for metastasis and a driver of treatment rationale and design. Radiotherapy is often utilized post-operatively to improve locoregional control or as a primary therapy in unresectable disease. Here we aim to review the role of radiotherapy in the management of this malignancy with a focus on target delineation and treatment regimens in the definitive, recurrent, and metastatic settings.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.