Evidence map›Paper›PMID 34944945›Full record

ArticleCancers2021

Anti-PD-1 Therapy with Adjuvant Ablative Fractional Laser Improves Anti-Tumor Response in Basal Cell Carcinomas.

Uffe Høgh Olesen, Martin Wiinberg, Catharina Margrethe Lerche, Ditte Elisabeth Jæhger, Thomas Lars Andresen, Merete Haedersdal

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. An immunocompetent transplantable mouse model of basal cell carcinoma.JID innovations : skin science from molecules to population health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Uffe Høgh OlesenDepartment of Dermatology, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Nielsine Nielsens Vej 17, 2400 Copenhagen, Denmark.ORCID 0000-0002-4578-684X
Martin WiinbergDepartment of Health Technology, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.ORCID 0000-0001-6999-0557
Catharina Margrethe LercheDepartment of Dermatology, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Nielsine Nielsens Vej 17, 2400 Copenhagen, Denmark.ORCID 0000-0003-3653-6424
Ditte Elisabeth JæhgerDepartment of Health Technology, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
Thomas Lars AndresenDepartment of Health Technology, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
Merete HaedersdalDepartment of Dermatology, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Nielsine Nielsens Vej 17, 2400 Copenhagen, Denmark.ORCID 0000-0003-1250-2035
Technical University of Denmark · DKFrederiksberg Hospital · DKUniversity of Copenhagen · DK

Funding

LEO Foundation LF18045
6 · The paper itself

Abstract

The efficacy of anti-programmedcelldeath1therapy (aPD-1), which was recently approved for basal cell carcinoma (BCC) treatment, can be enhanced by adjuvant ablative fractional laser (AFL) in syngeneic murine tumor models. In this explorative study, we aimed to assess locally applied AFL as an adjuvant to systemic aPD-1 treatment in a clinically relevant autochthonous BCC model. BCC tumors (

Indexed as

ablative fractional laserautochthonous cancer modelbasal cell carcinomaimmunotherapyprogrammed cell death-1 inhibitor

Identifiers

PMID34944945
PMCPMC8699063
OpenAlexW4200612700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.