Evidence map›Paper›PMID 34944869›Full record

ArticleCancers2021

Interstitial High-Dose-Rate Brachytherapy of Liver Metastases in Oligometastatic Patients.

Franziska Walter, Maya Rottler, Lukas Nierer, Guillaume Landry, Justus Well, Paul Rogowski, Konrad Mohnike, Max Seidensticker, Jens Ricke, Claus Belka and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Franziska WalterDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Maya RottlerDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Lukas NiererDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0001-9273-1625
Guillaume LandryDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Justus WellDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Paul RogowskiDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0003-3351-8896
Konrad MohnikeDiagnostisch Therapeutisches Zentrum (DTZ), 10243 Berlin, Germany.
Max SeidenstickerDepartment of Radiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0002-2481-5410
Jens RickeDepartment of Radiology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Claus BelkaDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, University Hospital, Ludwig Maximilian University, 81377 Munich, Germany.ORCID 0000-0001-8709-7252
Ludwig-Maximilians-Universität München · DEDiagnostic and Treatment Centre Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local ablative treatments have emerged as a promising treatment strategy for patients with oligometastatic disease. Among others, interstitial brachytherapy (iBT) is an upcoming treatment option for unresectable liver metastases. We report the feasibility and oncologic outcome of iBT of oligometastatic liver metastases performed in patients with limited tumor burdens in a high-volume center. Patients undergoing iBT between August 2017and March 2019 were included. A retrospective analysis of patient outcomes and treatment complications was performed. Patients treated for metastatic colorectal carcinoma (CRC) were compared to other histologies. A total of 141 iBT procedures were performed in 106 patients (male:52; female:54) and 244 liver metastases. Overall, 51% (54/106) of patients had a diagnosis of metastatic CRC. The median follow-up was 9 months, and overall survival (OS) was 92.3% at 6 months and 76.3% at 12 months. Local-relapse-free survival (LRFS) was 88.4% at 6 months and 71.5% at 12 months, with a significant difference between patients with CRC (84.1% and 50.6%) versus other histologies (92.4% and 92.4%,

Indexed as

brachytherapyliverlocal controlmetastasesoutcomeradiotherapysurvival

Identifiers

PMID34944869
PMCPMC8699459
OpenAlexW4200439164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.