Evidence map›Paper›PMID 34944823›Full record

ArticleCancers2021

Acute and Long-Term Outcomes of ST-Elevation Myocardial Infarction in Cancer Patients, a 'Real World' Analysis with 175,000 Patients.

Stefan A Lange, Jannik Feld, Leonie Kühnemund, Jeanette Köppe, Lena Makowski, Christiane M Engelbertz, Joachim Gerß, Patrik Dröge, Thomas Ruhnke, Christian Günster and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cardiogenic shock among cancer patients.Frontiers in cardiovascular medicine · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Stefan A LangeCardiol, Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, D-48149 Muenster, Germany.
Jannik FeldInstitute of Biostatistics and Clinical Research, University of Muenster, D-48149 Muenster, Germany.ORCID 0000-0003-1555-9192
Leonie KühnemundCardiol, Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0002-3430-5895
Jeanette KöppeInstitute of Biostatistics and Clinical Research, University of Muenster, D-48149 Muenster, Germany.ORCID 0000-0003-3640-2995
Lena MakowskiCardiol, Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0002-4672-1351
Christiane M EngelbertzCardiol, Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0002-2685-5117
Joachim GerßInstitute of Biostatistics and Clinical Research, University of Muenster, D-48149 Muenster, Germany.ORCID 0000-0003-3489-683X
Patrik DrögeAOK Research Institute (WIdO), D-10178 Berlin, Germany.
Thomas RuhnkeAOK Research Institute (WIdO), D-10178 Berlin, Germany.
Christian GünsterAOK Research Institute (WIdO), D-10178 Berlin, Germany.
Eva FreisingerCardiol, Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, D-48149 Muenster, Germany.
Holger ReineckeCardiol, Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, D-48149 Muenster, Germany.
University Hospital Münster · DEWissenschaftliches Institut der AOK · DE

Funding

G-BA, Innovationsfonds 01VSF18051
6 · The paper itself

Abstract

backgroundAcute myocardial infarction (AMI) and cancer are common and serious diseases. As the prognosis and treatment of both diseases has improved, more cancer patients will suffer an AMI. Unfortunately, data on these "double hit" patients is scarce.

methodsFrom the largest public German health insurance, anonymized data of all patients with pre-existing cancer who were hospitalized due to ST-elevation MI (STEMI) between 2010 and 2017 were analyzed and followed-up until 2018.

resultsOf 175,262 STEMI patients, 27,213 had pre-existing cancer (15.5%). Most frequent were skin (24.9%), prostate (17.0%), colon (11.0%), breast (10.9%), urinary tract (10.6%), and lung cancer (5.2%). STEMI patients with malignancies were older and presented more often with coronary three-vessel disease, atrial arrhythmias, chronic kidney disease, chronic heart failure, cerebrovascular and peripheral artery disease (PAD, each

conclusionIn this large "real world" data, prognosis after STEMI in cancer patients was markedly reduced but differed widely between cancer types. Of note, no withholding of interventional treatments in cancer patients could be observed.

Indexed as

cancer diseaseco-morbiditieshealth service researchmortalitySTEMI

Identifiers

PMID34944823
PMCPMC8699199
OpenAlexW4200435281

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.