Evidence map›Paper›PMID 34944733›Full record

ReviewBiomedicines2021

Tissue Engineering of the Urethra: From Bench to Bedside.

Dusan Pastorek, Martina Culenova, Maria Csobonyeiova, Veronika Skuciova, Lubos Danisovic, Stanislav Ziaran

Abstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Description of the Human Penile Urethra Epithelium.Medicina (Kaunas, Lithuania) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. [Research advances of three-dimensional bioprinting technology in urinary system tissue engineering].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dusan PastorekDepartment of Urology, University Hospital Bratislava, Pazitkova 4, 821 01 Bratislava, Slovakia.ORCID 0000-0003-2205-7772
Martina CulenovaInstitute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.
Maria CsobonyeiovaInstitute of Histology and Embryology, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.
Veronika SkuciovaDepartment of Histology and Embryology, Jessenius Faculty of Medicine in Martin, Comenius University, Mala Hora 4, 036 01 Martin, Slovakia.
Lubos DanisovicInstitute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia.ORCID 0000-0002-5074-9621
Stanislav ZiaranNational Institute of Rheumatic Diseases, Nabrezie I. Krasku 4, 921 12 Piestany, Slovakia.ORCID 0000-0002-5487-0875

Funding

European Regional Development Fund ITMS2014+: 313011V358
6 · The paper itself

Abstract

Tissue engineering (TE) is a promising approach for repair/substitution of damaged tissues and organs. Urethral strictures are common and serious health conditions that impair quality of life and may lead to serious organ damage. The search for ideal materials for urethral repair has led to interest of scientists and surgeons in urethral TE. Over the last decades, a significant amount of preclinical studies and considerable progress have been observed. In contrast, urethral TE has made slow progress in clinical practice so far. To address this, we conducted a systematic review of the literature on clinical applications of TE constructs for urethral repair in the last three decades. In summary, the TE approach is promising and effective, but many issues remain that need to be addressed for broader adoption of TE in urethral repair. Better design of trials, better cooperation of research groups and centralization could lead to reduction of costs and slowly proceed to commercialization and routine use of TE products for urethral reconstruction.

Indexed as

scaffoldsstem cellstissue engineeringurethraurethral reconstructionurethral stricture

Identifiers

PMID34944733
PMCPMC8698949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.