Evidence map›Paper›PMID 34944684›Full record

ArticleBiomedicines2021

Catalase Activity in Keratinocytes, Stratum Corneum, and Defatted Algae Biomass as a Potential Skin Care Ingredient.

Michal Szczepanczyk, Tautgirdas Ruzgas, Fredrika Gullfot, Anna Gustafsson, Sebastian Björklund

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michal SzczepanczykDepartment of Biomedical Science, Malmö University, 214 32 Malmö, Sweden.
Tautgirdas RuzgasDepartment of Biomedical Science, Malmö University, 214 32 Malmö, Sweden.ORCID 0000-0003-0304-7528
Fredrika GullfotSimris Alg AB, 276 50 Hammenhög, Sweden.
Anna GustafssonDepartment of Biomedical Science, Malmö University, 214 32 Malmö, Sweden.ORCID 0000-0001-9847-5132
Sebastian BjörklundDepartment of Biomedical Science, Malmö University, 214 32 Malmö, Sweden.ORCID 0000-0001-6254-8539
Malmö University · SESimris Alg (Sweden) · SE

Funding

The Knowledge Foundation 202100-4920
6 · The paper itself

Abstract

The generation of reactive oxygen species presents a destructive challenge for the skin organ and there is a clear need to advance skin care formulations aiming at alleviating oxidative stress. The aim of this work was to characterize the activity of the antioxidative enzyme catalase in keratinocytes and in the skin barrier (i.e., the stratum corneum). Further, the goal was to compare the activity levels with the corresponding catalase activity found in defatted algae biomass, which may serve as a source of antioxidative enzymes, as well as other beneficial algae-derived molecules, to be employed in skin care products. For this, an oxygen electrode-based method was employed to determine the catalase activity and the apparent kinetic parameters for purified catalase, as well as catalase naturally present in HaCaT keratinocytes, excised stratum corneum samples collected from pig ears with various amounts of melanin, and defatted algae biomass from the diatom

Indexed as

antioxidantsClark electrodeoxidative stressoxygen electrodeskin careskin organ

Identifiers

PMID34944684
PMCPMC8699009
OpenAlexW4200150304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.