Evidence map›Paper›PMID 34944672›Full record

ArticleBiomedicines2021

2D Projection Maps of WSS and OSI Reveal Distinct Spatiotemporal Changes in Hemodynamics in the Murine Aorta during Ageing and Atherosclerosis.

Kristina Andelovic, Patrick Winter, Thomas Kampf, Anton Xu, Peter Michael Jakob, Volker Herold, Wolfgang Rudolf Bauer, Alma Zernecke

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Exploring the relationship between hemodynamics and the immune microenvironment in carotid atherosclerosis: Insights from CFD and CyTOF technologies.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kristina AndelovicInstitute of Experimental Biomedicine, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-8869-8359
Patrick WinterExperimental Physics V, University of Würzburg, 97074 Würzburg, Germany.
Thomas KampfDiagnostic and Interventional Neuroradiology, University Hospital Würzburg, 97080 Würzburg, Germany.
Anton XuDepartment of Translational Research, Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, 97080 Würzburg, Germany.
Peter Michael JakobExperimental Physics V, University of Würzburg, 97074 Würzburg, Germany.
Volker HeroldExperimental Physics V, University of Würzburg, 97074 Würzburg, Germany.
Wolfgang Rudolf BauerInternal Medicine I, Cardiology, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-4652-7313
Alma ZerneckeInstitute of Experimental Biomedicine, University Hospital Würzburg, 97080 Würzburg, Germany.
Universitätsklinikum Würzburg · DEUniversity of Würzburg · DE

Funding

Deutsche Forschungsgemeinschaft ZE827/15-1, BA 1069/14-1, HE 7108/3-1Federal Ministry of Education and Research BMBF01, E01004
6 · The paper itself

Abstract

Growth, ageing and atherosclerotic plaque development alter the biomechanical forces acting on the vessel wall. However, monitoring the detailed local changes in wall shear stress (WSS) at distinct sites of the murine aortic arch over time has been challenging. Here, we studied the temporal and spatial changes in flow, WSS, oscillatory shear index (OSI) and elastic properties of healthy wildtype (WT,

Indexed as

4D flow MRIaortic archatherosclerosisflow dynamicsmappingmouseplaque characteristicsPWVWSS

Identifiers

PMID34944672
PMCPMC8698968
OpenAlexW4200351247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.