Evidence map›Paper›PMID 34944619›Full record

ArticleBiomedicines2021

Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats.

Zuzana Honetschlägerová, Lucie Hejnová, Jiří Novotný, Aleš Marek, Luděk Červenka

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zuzana HonetschlägerováCenter for Experimental Medicine, Institute for Clinical and Experimental Medicine, 1958/9 Vídeňská, CZ-140 00 Prague, Czech Republic.
Lucie HejnováDepartment of Physiology, Faculty of Science, Charles University, CZ-140 00 Prague, Czech Republic.
Jiří NovotnýDepartment of Physiology, Faculty of Science, Charles University, CZ-140 00 Prague, Czech Republic.
Aleš MarekDepartment of Synthesis of Radiolabeled Compounds, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, CZ-140 00 Prague, Czech Republic.ORCID 0000-0001-9031-8263
Luděk ČervenkaDepartment of Pathophysiology, 2nd Faculty of Medicine, Charles University, CZ-140 00 Prague, Czech Republic.
Charles University · CZCzech Academy of Sciences · CZInstitute of Clinical and Experimental Medicine · CZ

Funding

Czech Academy of Sciences RVO 61388963Ministry of Health NV 18-02-00053
6 · The paper itself

Abstract

Detailed mechanism(s) of the beneficial effects of renal denervation (RDN) on the course of heart failure (HF) remain unclear. The study aimed to evaluate renal vascular responsiveness to angiotensin II (ANG II) and to characterize ANG II type 1 (AT

Indexed as

ANG II receptorsaorto-caval fistulaheart failurerenal denervation

Identifiers

PMID34944619
PMCPMC8698780
OpenAlexW3215653055

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.