Evidence map›Paper›PMID 34944618›Full record

ArticleBiomedicines2021

Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A.

Cornelia Wiegand, Uta-Christina Hipler, Peter Elsner, Jörg Tittelbach

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  13. Review
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  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cornelia WiegandDepartment of Dermatology, University Hospital Jena, Erfurter Str. 35, 07743 Jena, Germany.
Uta-Christina HiplerDepartment of Dermatology, University Hospital Jena, Erfurter Str. 35, 07743 Jena, Germany.
Peter ElsnerDepartment of Dermatology, University Hospital Jena, Erfurter Str. 35, 07743 Jena, Germany.
Jörg TittelbachDepartment of Dermatology, University Hospital Jena, Erfurter Str. 35, 07743 Jena, Germany.ORCID 0000-0002-2223-150X
Jena University Hospital · DE

Funding

Dr. med. h.c. Erwin Braun Stiftung, Basel, Switzerland 07.04.2019
6 · The paper itself

Abstract

It is a general goal to improve wound healing, especially of chronic wounds. As light therapy has gained increasing attention, the positive influence on healing progression of water-filtered infrared A (wIRA), a special form of thermal radiation, has been investigated and compared to the detrimental effects of UV-B irradiation on wound closure in vitro. Models of keratinocyte and fibroblast scratches help to elucidate effects on epithelial and dermal healing. This study further used the simulation of non-optimal settings such as

Indexed as

collagendesmogleinfibroblastheat shock proteinkeratinocytepro-inflammatory cytokinesscratch assayUV-BwIRA (water-filtered infrared A)wound healing

Identifiers

PMID34944618
PMCPMC8698951
OpenAlexW3216692892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.