Evidence map›Paper›PMID 34944561›Full record

ArticleBiomedicines2021

WPK5, a Novel Kunitz-Type Peptide from the Leech

Yi-Zheng Zheng, Xiao-Ru Ji, Yun-Yang Liu, Shuai Jiang, Xiang-Ying Yu, Zhi-Ping Jia, Yue Zhao, Jun-Qiao Zhang, Jia-Li Zhang, Yi Kong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yi-Zheng ZhengSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.ORCID 0000-0001-6902-6450
Xiao-Ru JiSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Yun-Yang LiuSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Shuai JiangSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.ORCID 0000-0003-0239-1597
Xiang-Ying YuSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Zhi-Ping JiaSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Yue ZhaoSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Jun-Qiao ZhangSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Jia-Li ZhangSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.
Yi KongSchool of Life Science and Technology, China Pharmaceutical University, 24 Tong Jia Street, Nanjing 210009, China.ORCID 0000-0002-2329-7009
China Pharmaceutical University · CN

Funding

China Pharmaceutical University initiative program 446 CPU2018GY15
6 · The paper itself

Abstract

Kunitz-type proteins or peptides have been found in many blood-sucking animals, but the identity of them in leeches remained elusive. In the present study, five Kunitz-type peptides named WPK1-WPK5 were identified from the leech

Indexed as

AntithrombosisFXIa inhibitorKunitz-type peptidesLoop replacementtranscriptomeWhitmania pigra

Identifiers

PMID34944561
PMCPMC8698482
OpenAlexW3217786488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.