ReviewBiomolecules2021
In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes.
Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Enzyme Inhibition by Bioactive Compounds from Olive (Molecules (Basel, Switzerland) · 2026Pooled it
- In Vitro Antioxidant Activity and Dual-Target Inhibitory Effects of Dipyridamole on α-Amylase and α-Glucosidase: Molecular Mechanisms and Molecular Dynamics Simulations.Biomolecules · 2026Article
- Bio-Based Potential of Phenolic-Rich Fabaceae Seeds (Gonocytisus angulatus, Podocytisus caramanicus): Chemical Standardization, Functional Screening, and Molecular Insights.Chemistry & biodiversity · 2026Article
- A Node-Adaptive Feature Fusion Network for Drug-Target Interaction Prediction Based on Multi-View Graphs.Biomolecules · 2026Article
- Ultrasound-assisted and resin-based purification of bioactive polyphenols from peony (Paeonia ostii) pods: process optimization and α-glucosidase inhibitory activity.Ultrasonics sonochemistry · 2026Article
- Identification of Key Genes Involved in Lactic Acid Metabolism in Periodontitis Based on Bioinformatics Analysis.Journal of cellular and molecular medicine · 2026Article
- Genotoxicity of Artificial Sweetener Combinations: An Integrated Drosophila melanogaster SMART Assay and Computational Modeling Approach.Molecular genetics and genomics : MGG · 2026Article
- Computational pharmacovigilance of tranexamic acid: implications for intracerebral hemorrhage based on FAERS database and network toxicology.Frontiers in pharmacology · 2026Article
- α-Glucosidase-driven metabolism as a potential therapeutic vulnerability inFrontiers in microbiology · 2026Review
- Exploring Therapeutic Strategies against Monkeypox Virus Through Network Pharmacology and Bioinformatics Analysis.Current medicinal chemistry · 2026Article
- 1-Deoxynojirimycin Combined with Theaflavins Targets PTGS2/MMP9 to Exert a Synergistic Hypoglycemic Effect.Nutrients · 2025Article
- An update on current type 2 diabetes mellitus (T2DM) druggable targets and drugs targeting them.Molecular diversity · 2025Review
- Investigation of the potential of phytochemicals derived from citrus peels to inhibit digestive enzymes: an overture to the management of lifestyle diseases.Journal of enzyme inhibition and medicinal chemistry · 2025Review
- Peptides from 'Vaina Morada' Black Bean Inhibit α-Amylase and α-Glucosidase: A Combined In Silico-In Vitro Study.Foods (Basel, Switzerland) · 2025Article
- HPTLC based screening method for the evaluation of α-amylase inhibitory activity in edible flowers.Scientific reports · 2025Article
- Nanovesicles fromPharmaceuticals (Basel, Switzerland) · 2025Article
- Antidiabetic Properties of the Tropical TreePharmaceuticals (Basel, Switzerland) · 2025Review
- Thioflavonols as potent α-glucosidase inhibitors:Future medicinal chemistry · 2025Article
- Phytochemical Analysis and In-Vitro Biological Activities of Three WildMolecules (Basel, Switzerland) · 2025Article
- Integrating Multi-Domain Approach for Identification of Neo Anti-DHPS Inhibitors Against PathogenicBiology · 2025Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors, and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α-amylase enzymes inhibitors can suppress peaks of postprandial glucose with surplus adverse effects, leading to efforts devoted to urgently seeking new anti-diabetes drugs from natural sources for delayed starch digestion. This review attempts to explore 10 families e.g.,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.