Evidence map›Paper›PMID 34944512›Full record

ArticleBiomolecules2021

Characterization of Stress Responses in a

Derek G Epiney, Charlotte Salameh, Deirdre Cassidy, Luhan T Zhou, Joshua Kruithof, Rolan Milutinović, Tomas S Andreani, Aaron E Schirmer, Elyse Bolterstein

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Derek G EpineyDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Charlotte SalamehDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Deirdre CassidyDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Luhan T ZhouDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Joshua KruithofDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Rolan MilutinovićDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Tomas S AndreaniDepartment of Neurobiology, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-2967-9689
Aaron E SchirmerDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.
Elyse BoltersteinDepartment of Biology, Northeastern Illinois University, Chicago, IL 60625, USA.ORCID 0000-0002-1145-9138
Northeastern Illinois University · USNorthwestern University · US

Funding

Research Education CoreU54CA202997 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NAYLOR, KEITH BRIAN, TUSSING-HUMPHREYS, LISA · 2015 to 2024
$13.8M
Research Education CoreU54CA203000 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GIACHELLO, AIDA L · 2015 to 2024
$12.4M
The Chicago Cancer Health Equity Collaborative (ChicagoCHEC)U54CA202995 · NCI · NORTHEASTERN ILLINOIS UNIVERSITY · PI CIECIERSKI, CHRISTINA · 2015 to 2024
$9.5M
NCI NIH HHS U54CA202995NCI NIH HHS U54CA202997NCI NIH HHS U54CA203000
6 · The paper itself

Abstract

As organisms age, their resistance to stress decreases while their risk of disease increases. This can be shown in patients with Werner syndrome (WS), which is a genetic disease characterized by accelerated aging along with increased risk of cancer and metabolic disease. WS is caused by mutations in

Indexed as

MutationAgingAnimalsDisease Models, AnimalDrosophilaDrosophila ProteinsExonucleasesFemaleHumansMaleOxidative StressSleepWerner SyndromeWerner Syndrome HelicaseDrosophila ProteinsExonucleasesWerner Syndrome HelicaseWRNexo protein, DrosophilaWRN protein, humanDrosophilastressWerner syndrome

Identifiers

PMID34944512
PMCPMC8699552
OpenAlexW4200129972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.