Evidence map›Paper›PMID 34944390›Full record

ArticleBiomolecules2021

Altered Steroidome in Women with Gestational Diabetes Mellitus: Focus on Neuroactive and Immunomodulatory Steroids from the 24th Week of Pregnancy to Labor.

Leona Ondřejíková, Antonín Pařízek, Patrik Šimják, Daniela Vejražková, Marta Velíková, Kateřina Anderlová, Michala Vosátková, Hana Krejčí, Michal Koucký, Radmila Kancheva and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Leona OndřejíkováInstitute of Endocrinology, 116 94 Prague, Czech Republic.
Antonín PařízekDepartment of Gynecology and Obstetrics, First Faculty of Medicine, General University Hospital in Prague, Charles University in Prague, 128 08 Prague, Czech Republic.
Patrik ŠimjákDepartment of Gynecology and Obstetrics, First Faculty of Medicine, General University Hospital in Prague, Charles University in Prague, 128 08 Prague, Czech Republic.
Daniela VejražkováInstitute of Endocrinology, 116 94 Prague, Czech Republic.ORCID 0000-0003-2799-2874
Marta VelíkováInstitute of Endocrinology, 116 94 Prague, Czech Republic.
Kateřina AnderlováDepartment of Gynecology and Obstetrics, First Faculty of Medicine, General University Hospital in Prague, Charles University in Prague, 128 08 Prague, Czech Republic.
Michala VosátkováInstitute of Endocrinology, 116 94 Prague, Czech Republic.
Hana KrejčíDepartment of Gynecology and Obstetrics, First Faculty of Medicine, General University Hospital in Prague, Charles University in Prague, 128 08 Prague, Czech Republic.
Michal KouckýDepartment of Gynecology and Obstetrics, First Faculty of Medicine, General University Hospital in Prague, Charles University in Prague, 128 08 Prague, Czech Republic.
Radmila KanchevaInstitute of Endocrinology, 116 94 Prague, Czech Republic.
Michaela DuškováInstitute of Endocrinology, 116 94 Prague, Czech Republic.ORCID 0000-0002-4781-1447
Markéta VaňkováInstitute of Endocrinology, 116 94 Prague, Czech Republic.ORCID 0000-0003-1883-7274
Josef BulantInstitute of Endocrinology, 116 94 Prague, Czech Republic.
Martin HillInstitute of Endocrinology, 116 94 Prague, Czech Republic.
Institute of Endocrinology · CZCharles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is a complication in pregnancy, but studies focused on the steroidome in patients with GDM are not available in the public domain. This article evaluates the steroidome in GDM+ and GDM- women and its changes from 24 weeks (± of gestation) to labor. The study included GDM+ (

Indexed as

20-Hydroxysteroid DehydrogenasesChromatography, GasCytochrome P-450 CYP3ADiabetes, GestationalFemaleHumansMetabolomicsOxidoreductasesPregnancyPregnancy Trimester, SecondSteroid 17-alpha-HydroxylaseSteroidsTandem Mass Spectrometry20-Hydroxysteroid Dehydrogenases3 alpha-beta, 20 beta-hydroxysteroid dehydrogenase3-oxo-5 beta-steroid delta 4-dehydrogenaseCYP17A1 protein, humanCYP3A7 protein, humanCytochrome P-450 CYP3AOxidoreductasesSteroid 17-alpha-HydroxylaseSteroidsgas chromatography-tandem mass spectrometrygestational agegestational diabetes mellitusimmunoprotective steroidsmaternal bloodmixed cord bloodneuroactive steroidssteroidome

Identifiers

PMID34944390
PMCPMC8698588
OpenAlexW3215583898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.