Evidence map›Paper›PMID 34944375›Full record

ArticleAnimals : an open access journal from MDPI2021

Utero-Placental Immune Milieu during Normal and Aglepristone-Induced Parturition in the Dog.

Miguel Tavares Pereira, Renata Nowaczyk, Selim Aslan, Serhan S Ay, Mariusz P Kowalewski

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miguel Tavares PereiraInstitute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich (UZH), 8057 Zurich, Switzerland.ORCID 0000-0002-0537-5675
Renata NowaczykDepartment of Biostructure and Animal Physiology, Division of Histology and Embryology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-366 Wroclaw, Poland.
Selim AslanDepartment of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Near East University, Nicosia 99138, North Cyprus, Turkey.
Serhan S AyDepartment of Obstetrics and Gynecology, Ondokuz Mayıs University, Atakum 55200, Samsun, Turkey.
Mariusz P KowalewskiInstitute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich (UZH), 8057 Zurich, Switzerland.ORCID 0000-0002-4565-7714

Funding

Swiss National Science Foundation 31003A_182481
6 · The paper itself

Abstract

Maternal immunotolerance is required for the maintenance of pregnancy, in sharp contrast with the uterine pro-inflammatory activity observed during parturition in several species. Correspondingly, in the dog, increased immune signaling at term has been suggested, but a deeper understanding of the uterine immune milieu is still missing. Thus, the availability of 30 immune-related factors was assessed in utero-placental samples collected during post-implantation (days 18-25 of pregnancy) and mid-gestation (days 35-40) stages, and at the time of prepartum luteolysis. Gene expression and/or protein localization studies were employed. Samples collected from antigestagen (aglepristone)-treated dogs were further analyzed. Progression of pregnancy was associated with the downregulation of

Indexed as

aglepristonedog (Canis lupus familiaris)immune systemparturitionutero-placental

Identifiers

PMID34944375
PMCPMC8697996

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.