Evidence map›Paper›PMID 34944281›Full record

ArticleAnimals : an open access journal from MDPI2021

Myocardial Injury Complicated by Systolic Dysfunction in a COVID-19-Positive Dog.

Giovanni Romito, Teresa Bertaglia, Luigi Bertaglia, Nicola Decaro, Annamaria Uva, Gianluca Rugna, Ana Moreno, Giacomo Vincifori, Francesco Dondi, Alessia Diana and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Giovanni RomitoDepartment of Veterinary Medical Sciences, Alma Mater Studiorum-University of Bologna, 40064 Bologna, Italy.ORCID 0000-0003-3927-1601
Teresa BertagliaClinica Veterinaria Santa Teresa, 41032 Cavezzo, Italy.
Luigi BertagliaClinica Veterinaria Santa Teresa, 41032 Cavezzo, Italy.
Nicola DecaroDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.ORCID 0000-0001-6348-7969
Annamaria UvaDepartment of Veterinary Medicine, University of Bari, 70010 Valenzano, Italy.
Gianluca RugnaIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini", 25124 Brescia, Italy.ORCID 0000-0001-7437-1929
Ana MorenoIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini", 25124 Brescia, Italy.ORCID 0000-0002-8497-9708
Giacomo VinciforiIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", 64100 Teramo, Italy.ORCID 0000-0002-5956-4607
Francesco DondiDepartment of Veterinary Medical Sciences, Alma Mater Studiorum-University of Bologna, 40064 Bologna, Italy.ORCID 0000-0001-8259-6458
Alessia DianaDepartment of Veterinary Medical Sciences, Alma Mater Studiorum-University of Bologna, 40064 Bologna, Italy.ORCID 0000-0003-1709-3920
Mario CiponeDepartment of Veterinary Medical Sciences, Alma Mater Studiorum-University of Bologna, 40064 Bologna, Italy.
University of Bologna · ITIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" · ITUniversity of Bari Aldo Moro · ITIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A six-year-old Cavalier King Charles spaniel was referred with a two-month history of severe exercise intolerance and syncope. Clinical signs had developed during a local wave of coronavirus disease (COVID-19) two weeks after its family members had manifested symptoms of this viral disease and their positivity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed. Cardiologic assessment documented myocardial injury complicated by systolic dysfunction. An extensive diagnostic work-up allowed us to rule out common causes of myocardial compromise, both infective and not. Accordingly, serological and molecular tests aimed at diagnosing SARS-CoV-2 infection were subsequently performed, especially in light of the dog's peculiar history. Results of such tests, interpreted in the light of previous findings and current knowledge from human medicine, supported a presumptive diagnosis of COVID-19-associated myocardial injury, a clinical entity hitherto poorly described in this species.

Indexed as

caninedilated cardiomyopathy phenotypeechocardiographymyocarditisSARS-CoV-2

Identifiers

PMID34944281
PMCPMC8697878
OpenAlexW4200397600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.