Evidence map›Paper›PMID 34944266›Full record

ReviewAnimals : an open access journal from MDPI2021

Managing Gut Microbiota through In Ovo Nutrition Influences Early-Life Programming in Broiler Chickens.

Abdelrazeq M Shehata, Vinod K Paswan, Youssef A Attia, Abdel-Moneim Eid Abdel-Moneim, Mohammed Sh Abougabal, Mohamed Sharaf, Reda Elmazoudy, Wejdan T Alghafari, Mohamed A Osman, Mayada R Farag and 1 more

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  4. Effects ofAnimals : an open access journal from MDPI · 2026
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  16. A Mini-Review on Multi-Hurdle Control ofAnimals : an open access journal from MDPI · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdelrazeq M ShehataDepartment of Dairy Science and Food Technology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi 221005, India.ORCID 0000-0002-1492-2052
Vinod K PaswanDepartment of Dairy Science and Food Technology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi 221005, India.
Youssef A AttiaAgriculture Department, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0001-6505-3240
Abdel-Moneim Eid Abdel-MoneimNuclear Research Center, Biological Applications Department, Egyptian Atomic Energy Authority, Abu-Zaabal 13759, Egypt.ORCID 0000-0002-0199-6298
Mohammed Sh AbougabalDepartment of Animal Production, Faculty of Agriculture, Al-Azhar University, Cairo 11651, Egypt.
Mohamed SharafDepartment of Biochemistry and Molecular Biology, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-5891-7378
Reda ElmazoudyBiology Department, College of Science, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID 0000-0002-4704-7741
Wejdan T AlghafariClinical Nutrition Department, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Mohamed A OsmanBiology Department, College of Science, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Mayada R FaragForensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt.
Mahmoud AlagawanyPoultry Department, Agriculture Faculty, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-8020-0971

Funding

King Abdulaziz University FP-071-43 H
6 · The paper itself

Abstract

The chicken gut is the habitat to trillions of microorganisms that affect physiological functions and immune status through metabolic activities and host interaction. Gut microbiota research previously focused on inflammation; however, it is now clear that these microbial communities play an essential role in maintaining normal homeostatic conditions by regulating the immune system. In addition, the microbiota helps reduce and prevent pathogen colonization of the gut via the mechanism of competitive exclusion and the synthesis of bactericidal molecules. Under commercial conditions, newly hatched chicks have access to feed after 36-72 h of hatching due to the hatch window and routine hatchery practices. This delay adversely affects the potential inoculation of the healthy microbiota and impairs the development and maturation of muscle, the immune system, and the gastrointestinal tract (GIT). Modulating the gut microbiota has been proposed as a potential strategy for improving host health and productivity and avoiding undesirable effects on gut health and the immune system. Using early-life programming via in ovo stimulation with probiotics and prebiotics, it may be possible to avoid selected metabolic disorders, poor immunity, and pathogen resistance, which the broiler industry now faces due to commercial hatching and selection pressures imposed by an increasingly demanding market.

Indexed as

early-life programminggut microbiotain ovoprebioticsprobiotics

Identifiers

PMID34944266
PMCPMC8698130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.