Evidence map›Paper›PMID 34944238›Full record

ArticleAnimals : an open access journal from MDPI2021

Alternatives in Education-Evaluation of Rat Simulators in Laboratory Animal Training Courses from Participants' Perspective.

Melanie Humpenöder, Giuliano M Corte, Marcel Pfützner, Mechthild Wiegard, Roswitha Merle, Katharina Hohlbaum, Nancy A Erickson, Johanna Plendl, Christa Thöne-Reineke

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. A Novel 3D-Printed Mouse Model for Surgical Training: Multicenter Construct, Face, and Content Validation Study.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  4. Long-Term Experiences of Basic Education in Laboratory Animal Science.Animals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melanie HumpenöderInstitute of Animal Welfare, Department of Veterinary Medicine, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, 14163 Berlin, Germany.
Giuliano M CorteInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0002-1783-0444
Marcel PfütznerInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, Germany.
Mechthild WiegardInstitute of Animal Welfare, Department of Veterinary Medicine, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-1934-9187
Roswitha MerleInstitute for Veterinary Epidemiology and Biostatistics, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-8688-2926
Katharina HohlbaumInstitute of Animal Welfare, Department of Veterinary Medicine, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0001-6681-9367
Nancy A EricksonInstitute of Animal Welfare, Department of Veterinary Medicine, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, 14163 Berlin, Germany.
Johanna PlendlInstitute of Veterinary Anatomy, Department of Veterinary Medicine, Freie Universität Berlin, 14195 Berlin, Germany.
Christa Thöne-ReinekeInstitute of Animal Welfare, Department of Veterinary Medicine, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, 14163 Berlin, Germany.

Funding

German Centre for the Protection of Laboratory Animals 1328-565
6 · The paper itself

Abstract

In laboratory animal science (LAS) education and training, five simulators are available for exercises on handling and routine procedures on the rat, which is-beside mice-the most commonly used species in LAS. Since these simulators may have high potential in protecting laboratory rats, the aim of this study is to investigate the simulators' impact on the 3R (replace, reduce, refine) principle in LAS education and training. Therefore, the simulators were evaluated by 332 course participants in 27 different LAS courses via a practical simulator training workshop and a paper-based two-part questionnaire-both integrated in the official LAS course schedule. The results showed a high positive resonance for simulator training and it was considered especially useful for the inexperienced. However, the current simulators may not completely replace exercises on live animals and improvements regarding more realistic simulators are demanded. In accordance with literature data on simulator-use also in other fields of education, more research on simulators and new developments are needed, particularly with the aim for a broad implementation in LAS education and training benefiting all 3Rs.

Indexed as

3R principlealternativeEU Directivehumane educationlaboratory animalslaboratory animals science coursesrefinementSimulRATorsurveytraining

Identifiers

PMID34944238
PMCPMC8698197

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.