ReviewAnimals : an open access journal from MDPI2021
Experimental Applications and Factors Involved in Validating Thermal Windows Using Infrared Thermography to Assess the Health and Thermostability of Laboratory Animals.
Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Grimace scale, burrowing, and nest building for the assessment of post-surgical pain in mice and rats-A systematic review.Frontiers in veterinary science · 2022Pooled it
- Perioperative analgesia and clinical safety of dexketoprofen in dogs undergoing ovariohysterectomy.Open veterinary journal · 2026Article
- Distal Venous Arterialization Modulates Autophagy-Related Markers in Skeletal Muscle in a Rat Hindlimb Ischemia Model.Vascular health and risk management · 2026Article
- Social enrichment mitigates facial expressions and physiological indicators of short-term stress in horses.PloS one · 2026Article
- From Sensors to Sustainability: Integrating Welfare, Management, and Climate Resilience in Small Ruminant Farm Systems.Animals : an open access journal from MDPI · 2025Review
- Thermal imaging in biomedical research: a non-invasive technology for animal models.Frontiers in veterinary science · 2025Review
- Evaluation of the surface thermal response of peripheral nerve blocks in dogs undergoing trauma or orthopedic surgery.Frontiers in veterinary science · 2025Article
- Hypothalamic Neuromodulation and Control of the Dermal Surface Temperature of Livestock during Hyperthermia.Animals : an open access journal from MDPI · 2024Review
- Use of Infrared Thermography and Heart Rate Variability to Evaluate Autonomic Activity in Domestic Animals.Animals : an open access journal from MDPI · 2024Review
- Utilization of Infrared Thermography in Assessing Thermal Responses of Farm Animals under Heat Stress.Animals : an open access journal from MDPI · 2024Review
- Hypothalamic Neuromodulation of Hypothermia in Domestic Animals.Animals : an open access journal from MDPI · 2024Review
- Thermal Imaging as a Method to Indirectly Assess Peripheral Vascular Integrity and Tissue Viability in Veterinary Medicine: Animal Models and Clinical Applications.Animals : an open access journal from MDPI · 2023Review
- It's cool to be stressed: body surface temperatures track sympathetic nervous system activation during acute stress.The Journal of experimental biology · 2023Article
- Thermal Response of Laboratory Rats (Animals : an open access journal from MDPI · 2023Article
- Influence of Heat Stress on Body Temperatures Measured by Infrared Thermography, Blood Metabolic Parameters and Its Correlation in Sheep.Metabolites · 2023Article
- The Role of Brown Adipose Tissue and Energy Metabolism in Mammalian Thermoregulation during the Perinatal Period.Animals : an open access journal from MDPI · 2023Review
- Strategies and Mechanisms of Thermal Compensation in Newborn Water Buffaloes.Animals : an open access journal from MDPI · 2023Review
- Assessment of Pain and Inflammation in Domestic Animals Using Infrared Thermography: A Narrative Review.Animals : an open access journal from MDPI · 2023Review
- Effect of different masses, ages, and coats on the thermoregulation of dogs before and after exercise across different seasons.Veterinary research communications · 2023Article
- The impact of stress and anesthesia on animal models of infectious disease.Frontiers in veterinary science · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaluating laboratory animals' health and thermostability are fundamental components of all experimental designs. Alterations in either one of these parameters have been shown to trigger physiological changes that can compromise the welfare of the species and the replicability and robustness of the results obtained. Due to the nature and complexity of evaluating and managing the species involved in research protocols, non-invasive tools such as infrared thermography (IRT) have been adopted to quantify these parameters without altering them or inducing stress responses in the animals. IRT technology makes it possible to quantify changes in surface temperatures that are derived from alterations in blood flow that can result from inflammatory, stressful, or pathological processes; changes can be measured in diverse regions, called thermal windows, according to their specific characteristics. The principal body regions that were employed for this purpose in laboratory animals were the orbital zone (regio orbitalis), auricular pavilion (regio auricularis), tail (cauda), and the interscapular area (regio scapularis). However, depending on the species and certain external factors, the sensitivity and specificity of these windows are still subject to controversy due to contradictory results published in the available literature. For these reasons, the objectives of the present review are to discuss the neurophysiological mechanisms involved in vasomotor responses and thermogenesis via BAT in laboratory animals and to evaluate the scientific usefulness of IRT and the thermal windows that are currently used in research involving laboratory animals.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.