Evidence map›Paper›PMID 34944210›Full record

ArticleAnimals : an open access journal from MDPI2021

The Clinical Effect of Xylazine Premedication in Water Buffalo Calves (

Giulia Guerri, Ilaria Cerasoli, Paola Straticò, Ippolito De Amicis, Brunella Giangaspero, Vincenzo Varasano, Andrea Paolini, Augusto Carluccio, Lucio Petrizzi

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Surgical Description of Laparoscopic OvumAnimals : an open access journal from MDPI · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giulia GuerriFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.ORCID 0000-0002-3110-107X
Ilaria CerasoliClinica Veterinaria Borghesiana, Via di Vermicino 96, 00133 Roma, Italy.ORCID 0000-0003-0997-9676
Paola StraticòFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.
Ippolito De AmicisFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.
Brunella GiangasperoFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.
Vincenzo VarasanoFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.
Andrea PaoliniFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.
Augusto CarluccioFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.
Lucio PetrizziFaculty of Veterinary Medicine, University of Teramo, Località Piano D'Accio, 64100 Teramo, Italy.ORCID 0000-0001-7830-7545
University of Teramo · IT

Funding

Italian Ministry for Education, University and Research, Project "Demetra" (Dipartimenti di Eccellenza 2018-2022, ) CUP_C46C18000530001
6 · The paper itself

Abstract

Castration is one of the most frequently performed surgical procedures in livestock. All methods of castration are associated with a significant degree of pain, affecting the patients' welfare. Limited information on species-specific protocols in buffaloes is available. Considering the importance of this species and the scarcity of reports available, the objective of this study was to evaluate the effects of two different intramuscular doses of xylazine for premedication in water buffalo calves undergoing isoflurane maintenance anaesthesia for routine castration surgery. Twenty clinically healthy male water buffaloes undergoing bilateral orchiectomy were randomly assigned to two groups of 10 animals each: Group 1 was premedicated with xylazine 0.1 mg/kg bw i.m. and Group 2 was premedicated with xylazine 0.15 mg/kg bw i.m. Anaesthesia was induced by ketamine (2 mg/kg bw i.v.) and maintained with isoflurane-oxygen-air in both groups. The HR, RR, presence/absence of ataxia, sedation, depth of anaesthesia, muscle relaxation status, response to acoustic and tactile stimuli, eyelid reflex, extent of salivation and stimulus were evaluated every 5 min. Both protocols provided consistent sedation and were safe. Faster and more satisfactory sedation was recorded when xylazine was administered at 0.15 mg/kg bw i.m., leading us to recommend this dose for buffalo orchiectomy.

Indexed as

anaesthesiabuffaloescastrationisofluraneketaminexylazine

Identifiers

PMID34944210
PMCPMC8698050
OpenAlexW3217588122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.