Evidence map›Paper›PMID 34944018›Full record

ArticleCells2021

Mayaro Virus Non-Structural Protein 2 Circumvents the Induction of Interferon in Part by Depleting Host Transcription Initiation Factor IIE Subunit 2.

Ray Ishida, Jamie Cole, Joaquin Lopez-Orozco, Nawell Fayad, Alberto Felix-Lopez, Mohamed Elaish, Shu Yue Luo, Olivier Julien, Anil Kumar, Tom C Hobman

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Innate immune evasion by alphaviruses.Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ray IshidaDepartment of Medical Microbiology & Immunology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Jamie ColeDepartment of Cell Biology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Joaquin Lopez-OrozcoDepartment of Cell Biology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Nawell FayadDepartment of Cell Biology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Alberto Felix-LopezDepartment of Cell Biology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Mohamed ElaishDepartment of Cell Biology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0003-3628-5856
Shu Yue LuoDepartment of Biochemistry, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-6379-0308
Olivier JulienDepartment of Biochemistry, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0001-7068-7299
Anil KumarDepartment of Cell Biology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.ORCID 0000-0002-6179-4516
Tom C HobmanDepartment of Medical Microbiology & Immunology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2E1, Canada.
University of Alberta · CA

Funding

CIHR OV3-172302CIHR PJT-148699CIHR PJT-162417
6 · The paper itself

Abstract

Mayaro virus (MAYV) is an emerging mosquito-transmitted virus that belongs to the genus

Indexed as

Host-Pathogen InteractionsAlphavirusAnimalsCell LineCell NucleusDown-RegulationHumansInterferon Regulatory Factor-3InterferonsProtein BindingProtein SubunitsProtein TransportRNA Polymerase IITranscription Factors, TFIITranscription, GeneticViral Nonstructural ProteinsInterferon Regulatory Factor-3InterferonsIRF3 protein, humanProtein SubunitsRNA Polymerase IITranscription Factors, TFIItranscription factor TFIIEViral Nonstructural ProteinsalphavirusinterferonMAYVnsP2Rpb1TFIIE2

Identifiers

PMID34944018
PMCPMC8700540
OpenAlexW4200619221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.