Evidence map›Paper›PMID 34943935›Full record

ReviewCells2021

Molecular Biomarkers for Adrenoleukodystrophy: An Unmet Need.

Madison I J Honey, Yorrick R J Jaspers, Marc Engelen, Stephan Kemp, Irene C Huffnagel

Abstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy.Annals of clinical and translational neurology · 2026
    Review
  4. Observational
  5. Lipid signature in X-ALD: a comparison between phenotypes.Frontiers in molecular biosciences · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. A Phase 1 Study of Oral Vitamin DNeurology. Genetics · 2023
    Article
  12. Sex-specific newborn screening for X-linked adrenoleukodystrophy.Journal of inherited metabolic disease · 2023
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madison I J HoneyNeurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam University Medical Centers, Amsterdam Neuroscience, Vrije Universiteit, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-9422-8764
Yorrick R J JaspersLaboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam University Medical Centers, Amsterdam Gastroenterology Endocrinology Metabolism, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-9153-5734
Marc EngelenDepartment of Pediatric Neurology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam Neuroscience, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Stephan KempLaboratory Genetic Metabolic Diseases, Department of Clinical Chemistry, Amsterdam University Medical Centers, Amsterdam Gastroenterology Endocrinology Metabolism, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-2023-064X
Irene C HuffnagelDepartment of Pediatric Neurology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam Neuroscience, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Funding

Netherlands Organization for Health Research and Development 543002004 to SKNetherlands Organization for Scientific Research 016.196.310 to ME
6 · The paper itself

Abstract

X-linked adrenoleukodystrophy (ALD) is an inherited progressive neurometabolic disease caused by mutations in the

Indexed as

AdrenoleukodystrophyATP Binding Cassette Transporter, Subfamily D, Member 1BiomarkersGenetic Diseases, X-LinkedHumansATP Binding Cassette Transporter, Subfamily D, Member 1Biomarkersadrenoleukodystrophybiobankbiomarkerscerebral demyelinationclinical trialmyelopathynewborn screeningperoxisome

Identifiers

PMID34943935
PMCPMC8699919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.