Evidence map›Paper›PMID 34943892›Full record

ArticleCells2021

Association of

Chenglong Yu, Allison M Hodge, Ee Ming Wong, Jihoon Eric Joo, Enes Makalic, Daniel Schmidt, Daniel D Buchanan, John L Hopper, Graham G Giles, Melissa C Southey and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Longevity-associatedTranslational lung cancer research · 2026
    Article
  2. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Chenglong YuPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.ORCID 0000-0002-0546-2779
Allison M HodgeCancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC 3004, Australia.ORCID 0000-0001-5464-2197
Ee Ming WongPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
Jihoon Eric JooColorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, VIC 3010, Australia.
Enes MakalicCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0003-3017-0871
Daniel SchmidtDepartment of Data Science and AI, Faculty of Information Technology, Monash University, Clayton, VIC 3168, Australia.ORCID 0000-0002-1788-2375
Daniel D BuchananColorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0003-2225-6675
John L HopperCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC 3010, Australia.
Graham G GilesPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
Melissa C SoutheyPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
Pierre-Antoine DuguéPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
The University of Melbourne · AUMonash Health · AUMonash University · AUThe Royal Melbourne Hospital · AU

Funding

Australian NHMRC 251553Australian NHMRC 504711National Health and Medical Research Council 209057NHMRC 1011618NHMRC 1026892NHMRC 1027505NHMRC 1043616NHMRC 1050198NHMRC 1074383
6 · The paper itself

Abstract

Genetic variants in

Indexed as

AdultAgedCase-Control StudiesCohort StudiesCpG IslandsDNA MethylationFemaleForkhead Box Protein O3HumansLongevityMaleMiddle AgedNeoplasmsPolymorphism, Single NucleotideRisk FactorsSurvival AnalysisForkhead Box Protein O3FOXO3 protein, humanage-related outcomeepigeneticsFOXO3longevity-related SNPmatched case–control study

Identifiers

PMID34943892
PMCPMC8699522
OpenAlexW3215892976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.