ReviewCells2021
Genetic Engineering and Genome Editing for Improving Nitrogen Use Efficiency in Plants.
Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Plant-Associated Microbiomes: Crosstalk and Engineering to Improve Nutrient Use Efficiency (NUE) in Crops of Global Importance.Plants (Basel, Switzerland) · 2026Review
- Optimization of carbon and nitrogen utilization for enhanced photosynthesis, biomass and yield by coexpression of phosphoenolpyruvate carboxylase, aspartate aminotransferase and glutamine synthetase in Brassica juncea.Plant biotechnology journal · 2026Article
- The emerging impact of CRISPR and gene editing on global crop improvement.Transgenic research · 2026Review
- Enhancing cereal productivity via nitrogen use efficiency: from conventional breeding to modern genomics.Frontiers in genetics · 2026Review
- Decoding nitrogen uptake efficiency in maize and sorghum: insights from comparative gene regulatory networks.The Plant journal : for cell and molecular biology · 2025Article
- Nitrogen Use Efficiency in Agriculture: Integrating Biotechnology, Microbiology, and Novel Delivery Systems for Sustainable Agriculture.Plants (Basel, Switzerland) · 2025Review
- Differential effects of sole and phosphorus based nitrogen fertilizer sources on wheat growth and nutrient use efficiency.Scientific reports · 2025Article
- The Research Progress on the Effects of Phytohormones on Nitrogen Use Efficiency in Rice.Plants (Basel, Switzerland) · 2025Review
- Unlocking genetic hotspots: GWAS reveals key nitrogen responsive genomic regions and key genes for root and yield traits in indica rice.Molecular genetics and genomics : MGG · 2025Article
- Plant Nitrogen Assimilation: A Climate Change Perspective.Plants (Basel, Switzerland) · 2025Review
- Genome-Wide Analysis of the Aspartate Aminotransferase Family inInternational journal of molecular sciences · 2025Article
- Risk-appropriate regulations for gene-editing technologies.GM crops & food · 2024Article
- The recent genetic modification techniques for improve soil conservation, nutrient uptake and utilization.GM crops & food · 2024Review
- Bacterial endophyte Pseudomonas mosselii PR5 improves growth, nutrient accumulation, and yield of rice (Oryza sativa L.) through various application methods.BMC plant biology · 2024Article
- Nitrogen uptake dynamics of high and low protein wheat genotypes.Frontiers in plant science · 2024Article
- Hormonal Status of Transgenic Birch with a Pine Glutamine Synthetase Gene during Rooting In Vitro and Budburst Outdoors.Biomolecules · 2023Article
- Multi-Omics Analysis Reveals Synergistic Enhancement of Nitrogen Assimilation Efficiency via Coordinated Regulation of Nitrogen and Carbon Metabolism by Co-Application of Brassinolide and Pyraclostrobin inInternational journal of molecular sciences · 2023Article
- Impact of Intron and Retransformation on Transgene Expression in Leaf and Fruit Tissues of Field-Grown Pear Trees.International journal of molecular sciences · 2023Article
- Fruit Characteristics of Transgenic pear (Pyrus communis L.) Trees During Long-Term Field Trials.Plant foods for human nutrition (Dordrecht, Netherlands) · 2023Article
- Feeding the world: impacts of elevated [COHorticulture research · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Low nitrogen availability is one of the main limiting factors for plant growth and development, and high doses of N fertilizers are necessary to achieve high yields in agriculture. However, most N is not used by plants and pollutes the environment. This situation can be improved by enhancing the nitrogen use efficiency (NUE) in plants. NUE is a complex trait driven by multiple interactions between genetic and environmental factors, and its improvement requires a fundamental understanding of the key steps in plant N metabolism-uptake, assimilation, and remobilization. This review summarizes two decades of research into bioengineering modification of N metabolism to increase the biomass accumulation and yield in crops. The expression of structural and regulatory genes was most often altered using overexpression strategies, although RNAi and genome editing techniques were also used. Particular attention was paid to woody plants, which have great economic importance, play a crucial role in the ecosystems and have fundamental differences from herbaceous species. The review also considers the issue of unintended effects of transgenic plants with modified N metabolism, e.g., early flowering-a research topic which is currently receiving little attention. The future prospects of improving NUE in crops, essential for the development of sustainable agriculture, using various approaches and in the context of global climate change, are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.