Evidence map›Paper›PMID 34943794›Full record

ReviewCells2021

Pin1 as Molecular Switch in Vascular Endothelium: Notes on Its Putative Role in Age-Associated Vascular Diseases.

Francesca Fagiani, Marieva Vlachou, Daniele Di Marino, Ilaria Canobbio, Alice Romagnoli, Marco Racchi, Stefano Govoni, Cristina Lanni

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Beneficial Effects of PIN1 Inhibition on Diabetes Mellitus: A Concise Review.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  4. Subcellular Localization Guides eNOS Function.International journal of molecular sciences · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Francesca FagianiPharmacology Section, Department of Drug Sciences, University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.
Marieva VlachouPharmacology Section, Department of Drug Sciences, University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.
Daniele Di MarinoDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Ilaria CanobbioDepartment of Biology and Biotechnology, University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.
Alice RomagnoliDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Marco RacchiPharmacology Section, Department of Drug Sciences, University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.ORCID 0000-0002-7185-7808
Stefano GovoniPharmacology Section, Department of Drug Sciences, University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.
Cristina LanniPharmacology Section, Department of Drug Sciences, University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.ORCID 0000-0002-3061-4738
University of Pavia · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By controlling the change of the backbones of several cellular substrates, the peptidyl-prolyl

Indexed as

AgingAnimalsEndothelium, VascularHumansModels, BiologicalNIMA-Interacting Peptidylprolyl IsomeraseNitric OxideVascular DiseasesNIMA-Interacting Peptidylprolyl IsomeraseNitric Oxideagingnitric oxidenitric oxide synthasePin1vascular dementiavascular endothelium

Identifiers

PMID34943794
PMCPMC8699654
OpenAlexW3217361973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.