Evidence map›Paper›PMID 34943759›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Pan-Resistome Characterization of Uropathogenic

Arun Gonzales Decano, Kerry Pettigrew, Wilber Sabiiti, Derek J Sloan, Stella Neema, Joel Bazira, John Kiiru, Hellen Onyango, Benon Asiimwe, Matthew T G Holden

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Whole genome sequencing and genotypingAccess microbiology · 2024
    Article
  6. Monitoring Multi-Drug ResistantInfection and drug resistance · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Antimicrobial Resistance and Virulence Characteristics ofPathogens (Basel, Switzerland) · 2022
    Article
  12. Plasmids of the urinary microbiota.Access microbiology · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Arun Gonzales DecanoSchool of Medicine, University of St Andrews, St Andrews KY16 8BQ, UK.
Kerry PettigrewSchool of Medicine, University of St Andrews, St Andrews KY16 8BQ, UK.
Wilber SabiitiSchool of Medicine, University of St Andrews, St Andrews KY16 8BQ, UK.
Derek J SloanSchool of Medicine, University of St Andrews, St Andrews KY16 8BQ, UK.
Stella NeemaDepartment of Sociology and Anthropology, Makerere University, Kampala P.O. Box 7062, Uganda.
Joel BaziraFaculty of Medicine, Mbarara University of Science and Technology, Mbarara P.O. Box 410, Uganda.
John KiiruCentre of Microbiology Research, Kenya Medical Research Institute, Off Raila Odinga Way, Nairobi P.O. Box 54840 00200, Kenya.
Hellen OnyangoDepartment of Medical Microbiology, Jomo Kenyatta University of Agriculture and Technology, Nairobi P.O. Box 62 000, Kenya.
Benon AsiimweDepartment of Medical Microbiology, Makerere University College of Health Sciences, Kampala P.O. Box 7062, Uganda.
Matthew T G HoldenSchool of Medicine, University of St Andrews, St Andrews KY16 8BQ, UK.
University of St Andrews · GBMakerere University · UGJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KEMbarara University of Science and Technology · UG

Funding

Medical Research Council MR/S004785/1
6 · The paper itself

Abstract

Urinary tract infection (UTI) develops after a pathogen adheres to the inner lining of the urinary tract. Cases of UTIs are predominantly caused by several Gram-negative bacteria and account for high morbidity in the clinical and community settings. Of greater concern are the strains carrying antimicrobial resistance (AMR)-conferring genes. The gravity of a UTI is also determined by a spectrum of other virulence factors. This study represents a pilot project to investigate the burden of AMR among uropathogens in East Africa. We examined bacterial samples isolated in 2017-2018 from in- and out-patients in Kenya (KY) and Uganda (UG) that presented with clinical symptoms of UTI. We reconstructed the evolutionary history of the strains, investigated their population structure, and performed comparative analysis their pangenome contents. We found 55

Indexed as

antimicrobial resistancelmicpangenomepublic health

Identifiers

PMID34943759
PMCPMC8698711
OpenAlexW4226103637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.