Evidence map›Paper›PMID 34943756›Full record

ArticleAntibiotics (Basel, Switzerland)2021

DNA Methyltransferase HsdM Induce Drug Resistance on

Hongqian Chu, Yongfei Hu, Bing Zhang, Zhaogang Sun, Baoli Zhu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Multidrug-resistant tuberculosis.Nature reviews. Disease primers · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Heliyon · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hongqian ChuTranslational Medicine Center Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Yongfei HuCAS Key Laboratory of Pathogenic Microbiology & Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Bing ZhangCore Genomic Facility, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.
Zhaogang SunTranslational Medicine Center Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Baoli ZhuCAS Key Laboratory of Pathogenic Microbiology & Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Chinese Academy of Sciences · CNBeijing Chest Hospital · CNBeijing Institute of Genomics · CNCapital Medical University · CN

Funding

Beijing Municipal Natural Science Foundation 21JG0034National Natural Science Foundation 81871691, 31471203
6 · The paper itself

Abstract

Besides the genomic variants, epigenetic mechanisms such as DNA methylation also have an effect on drug resistance. This study aimed to investigate the methylomes of totally/extensively drug-resistant

Indexed as

DNA methyltransferasedrug resistanceHsdMMycobacterium tuberculosis

Identifiers

PMID34943756
PMCPMC8698436
OpenAlexW4200041214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.