Evidence map›Paper›PMID 34943737›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Early Diagnosis and Antibiotic Treatment Combined with Multicomponent Hemodynamic Support for Addressing a Severe Case of Lemierre's Syndrome.

Andreaserena Recchia, Marco Cascella, Sabrina Altamura, Felice Borrelli, Nazario De Nittis, Elisabetta Dibenedetto, Maria Labonia, Giovanna Pavone, Alfredo Del Gaudio

Open access · goldAbstract readCase Reports
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andreaserena RecchiaAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.ORCID 0000-0002-0376-7464
Marco CascellaAnesthesia and Pain Medicine Istituto Nazionale Tumori-IRCCS, Fondazione G. Pascale, 80100 Napoli, Italy.ORCID 0000-0002-5236-3132
Sabrina AltamuraAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Felice BorrelliAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Nazario De NittisAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Elisabetta DibenedettoAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Maria LaboniaMicrobiology and Virology, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Giovanna PavoneAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Alfredo Del GaudioAnesthesia and Intensive Care 2, IRCCS "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Casa Sollievo della Sofferenza · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 20-year-old man was admitted to the intensive care unit for septic shock due to Lemierre's syndrome. It is a rare syndrome that manifests as an upper respiratory infection, although systemic involvement, severe coagulopathy, and multi-organ failure can dangerously complicate the clinical picture. In this syndrome, sepsis-related neuroendocrine dysregulation and microcirculation impairment can have a rapid deleterious progression. Consequently, proper diagnosis, early source control, and appropriate antibiotics administration are mandatory to improve the prognosis. The intensive treatment is aimed at limiting organ damage through hemodynamic optimization. Remarkably, in septic shock due to Lemierre's syndrome, hemodynamic optimization can be achieved through the synergic effect of norepinephrine, argipressin, and hydrocortisone.

Indexed as

argipressinLemierre’s syndromenecrobacillosisnorepinephrinepost-anginal septicemiaseptic shock

Identifiers

PMID34943737
PMCPMC8698451
OpenAlexW4200386362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.