Evidence map›Paper›PMID 34943674›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Knowledge, Attitudes, Perception and Reported Practices of Healthcare Providers on Antibiotic Use and Resistance in Pregnancy, Childbirth and Children under Two in Lao PDR: A Mixed Methods Study.

Vanphanom Sychareun, Amphoy Sihavong, Anna Machowska, Xanded Onthongdee, Kongmany Chaleunvong, Bounxou Keohavong, Jaran Eriksen, Claudia Hanson, Manivanh Vongsouvath, Gaetano Marrone and 4 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Vanphanom SychareunFaculty of Public Health, University of Health Sciences (UHS), Vientiane 7444, Laos.
Amphoy SihavongVientiane Capital Health Department, Ministry of Health, Vientiane 01030, Laos.
Anna MachowskaDepartment of Global Public Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Xanded OnthongdeeLao Tropical and Public Health Institute, Ministry of Health, Vientiane 01030, Laos.
Kongmany ChaleunvongInstitute of Research and Education Development, UHS, Ministry of Health, Vientiane 01030, Laos.
Bounxou KeohavongFood and Drug Department, Ministry of Health, Vientiane 01030, Laos.
Jaran EriksenDepartment of Global Public Health, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0003-1146-5615
Claudia HansonDepartment of Global Public Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Manivanh VongsouvathLao-Oxford-Mahosot Hospital-Welcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane 01000, Laos.
Gaetano MarroneDepartment of Global Public Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Annelie BraunerDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
Mayfong MayxayInstitute of Research and Education Development, UHS, Ministry of Health, Vientiane 01030, Laos.
Sengchanh KounnavongLao Tropical and Public Health Institute, Ministry of Health, Vientiane 01030, Laos.
Cecilia Stålsby LundborgDepartment of Global Public Health, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0001-6525-1861
Karolinska Institutet · SEMinistry of Health · LAMahosot Hospital · LAKarolinska University Hospital · SEUniversity of Health Sciences Vientiane · LA

Funding

Karolinska Institute 2018-01027Swedish Research Council 2018-01027
6 · The paper itself

Abstract

backgroundOveruse and misuse of antibiotics contribute unnecessarily to antibiotic resistance (ABR), and are thereby global health threats. Inappropriate prescriptions of antibiotics during pregnancy, delivery and early childhood are widespread across the world. This study aimed to assess knowledge, attitudes, and reported practices of healthcare providers (HCPs) and to explore their perceptions regarding antibiotic use and ABR related to pregnancy, childbirth, and children under two in Lao PDR.

methodsThis is a mixed methods study with data collection in 2019 via structured interviews among 217 HCPs (medical doctors/assistant doctors, midwives/nurses, pharmacists/assistant pharmacists and drug sellers), who prescribed/dispensed antibiotics in one rural and one urban district in Vientiane province and individual qualitative interviews with 30 HCPs and stakeholders.

resultsOf the HCPs, 36% had below average knowledge regarding antibiotic use and ABR, and 67% reported prescribing antibiotics for uncomplicated vaginal delivery. Half of the HCPs did not believe that their prescribing contributed to ABR, and only 9% had participated in antibiotic education.

conclusionA substantial number of HCPs had suboptimal knowledge and prescribed antibiotics unnecessarily, thereby contributing to ABR. Continuous education and regular supervision of HCPs is recommended to improve the use of antibiotics related to pregnancy, childbirth, and young children.

Indexed as

antibioticantibiotic resistanceattitudechildren under twodeliveryhealthcare providerknowledgeLao PDRpracticepregnancy

Identifiers

PMID34943674
PMCPMC8698782
OpenAlexW3214965995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.