Evidence map›Paper›PMID 34943611›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer.

David C Rotzinger, Damien Racine, Fabio Becce, Elias Lahoud, Klaus Erhard, Salim A Si-Mohamed, Joël Greffier, Anaïs Viry, Loïc Boussel, Reto A Meuli and 3 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

David C RotzingerDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH 1011 Lausanne, Switzerland.ORCID 0000-0002-6321-3180
Damien RacineFaculty of Biology and Medicine (FBM), University of Lausanne (UNIL), CH 1015 Lausanne, Switzerland.
Fabio BecceDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH 1011 Lausanne, Switzerland.ORCID 0000-0001-8444-8504
Elias LahoudCT/AMI Research and Development, Philips Medical Systems, Haifa 31004, Israel.
Klaus ErhardPhilips GmbH Innovative Technologies, Philips Research Laboratories, 22335 Hamburg, Germany.
Salim A Si-MohamedRadiology Department, Hospices Civils de Lyon, 69500 Lyon, France.ORCID 0000-0003-0314-4010
Joël GreffierDepartment of Medical Imaging, CHU Nimes, University of Montpellier, 30900 Nimes, France.
Anaïs ViryFaculty of Biology and Medicine (FBM), University of Lausanne (UNIL), CH 1015 Lausanne, Switzerland.
Loïc BousselRadiology Department, Hospices Civils de Lyon, 69500 Lyon, France.
Reto A MeuliDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH 1011 Lausanne, Switzerland.ORCID 0000-0002-9573-3076
Yoad YagilCT/AMI Research and Development, Philips Medical Systems, Haifa 31004, Israel.
Pascal MonninFaculty of Biology and Medicine (FBM), University of Lausanne (UNIL), CH 1015 Lausanne, Switzerland.
Philippe C DouekRadiology Department, Hospices Civils de Lyon, 69500 Lyon, France.

Funding

European Union Horizon 2020 643694France Life Imaging (FLI) N/A
6 · The paper itself

Abstract

aimsTo evaluate spectral photon-counting CT's (SPCCT) objective image quality characteristics in vitro, compared with standard-of-care energy-integrating-detector (EID) CT.

methodsWe scanned a thorax phantom with a coronary artery module at 10 mGy on a prototype SPCCT and a clinical dual-layer EID-CT under various conditions of simulated patient size (small, medium, and large). We used filtered back-projection with a soft-tissue kernel. We assessed noise and contrast-dependent spatial resolution with noise power spectra (NPS) and target transfer functions (TTF), respectively. Detectability indices (d') of simulated non-calcified and lipid-rich atherosclerotic plaques were computed using the non-pre-whitening with eye filter model observer.

resultsSPCCT provided lower noise magnitude (9-38% lower NPS amplitude) and higher noise frequency peaks (sharper noise texture). Furthermore, SPCCT provided consistently higher spatial resolution (30-33% better TTF

conclusionsSPCCT outperformed EID-CT in detecting simulated coronary atherosclerosis and might enhance diagnostic accuracy by providing lower noise magnitude, markedly improved spatial resolution, and superior lipid core detectability.

Indexed as

cardiac imaging techniquescomputed tomography angiographycoronary vesselsimage quality enhancementphantoms imaging

Identifiers

PMID34943611
PMCPMC8700425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.