Evidence map›Paper›PMID 34943601›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Development of a Machine Learning Model to Distinguish between Ulcerative Colitis and Crohn's Disease Using RNA Sequencing Data.

Soo-Kyung Park, Sangsoo Kim, Gi-Young Lee, Sung-Yoon Kim, Wan Kim, Chil-Woo Lee, Jong-Lyul Park, Chang-Hwan Choi, Sang-Bum Kang, Tae-Oh Kim and 7 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 1 country.

Soo-Kyung ParkDivision of Gastroenterology, Department of Internal Medicine and Inflammatory Bowel Disease Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Korea.
Sangsoo KimDepartment of Bioinformatics, Soongsil University, Seoul 06978, Korea.
Gi-Young LeeDepartment of Bioinformatics, Soongsil University, Seoul 06978, Korea.
Sung-Yoon KimDepartment of Bioinformatics, Soongsil University, Seoul 06978, Korea.
Wan KimDepartment of Bioinformatics, Soongsil University, Seoul 06978, Korea.
Chil-Woo LeeMedical Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Korea.
Jong-Lyul ParkPersonalized Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.
Chang-Hwan ChoiDepartment of Internal Medicine, College of Medicine, Chung-Ang University, Seoul 04388, Korea.ORCID 0000-0001-7089-532X
Sang-Bum KangDepartment of Internal Medicine, College of Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea, Daejeon 34943, Korea.ORCID 0000-0002-1946-7896
Tae-Oh KimDepartment of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan 48108, Korea.
Ki-Bae BangDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan 31116, Korea.ORCID 0000-0002-9961-9318
Jaeyoung ChunDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID 0000-0002-4212-0380
Jae-Myung ChaDepartment of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University College of Medicine, Seoul 05278, Korea.
Jong-Pil ImDepartment of Internal Medicine and Liver Research Institute, College of Medicine, Seoul National University, Seoul 03080, Korea.ORCID 0000-0003-1584-0160
Kwang-Sung AhnFunctional Genome Institute, PDXen Biosystems Inc., Daejeon 34129, Korea.
Seon-Young KimPersonalized Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.
Dong-Il ParkDivision of Gastroenterology, Department of Internal Medicine and Inflammatory Bowel Disease Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Korea.
Soongsil University · KRKangbuk Samsung Hospital · KRChung-Ang University · KRDankook University · KRInje University Haeundae Paik Hospital · KRKorea Research Institute of Bioscience and Biotechnology · KRKyung Hee University Hospital at Gangdong · KRSeoul National University · KRThe Catholic University of Korea Daejeon St. Mary's Hospital · KRYonsei University · KR

Funding

National Research Foundation of Korea NRF- 2020R1A2B5B02002259
6 · The paper itself

Abstract

Crohn's disease (CD) and ulcerative colitis (UC) can be difficult to differentiate. As differential diagnosis is important in establishing a long-term treatment plan for patients, we aimed to develop a machine learning model for the differential diagnosis of the two diseases using RNA sequencing (RNA-seq) data from endoscopic biopsy tissue from patients with inflammatory bowel disease (

Indexed as

Crohn’s diseaseinflammatory bowel diseasemachine learningRNA sequencingulcerative colitis

Identifiers

PMID34943601
PMCPMC8700628
OpenAlexW4200103252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.