Evidence map›Paper›PMID 34943587›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Uterine Artery Embolization Combined with Subsequent Suction Evacuation as Low-Risk Treatment for Cesarean Scar Pregnancy.

Roxana Bohiltea, Ionita Ducu, Bianca Mihai, Ana-Maria Iordache, Bogdan Dorobat, Emilia Maria Vladareanu, Stefan-Marian Iordache, Alexia-Teodora Bohiltea, Nicolae Bacalbasa, Cristiana Eugenia Ana Grigorescu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Ectopic Intramural Isthmic Pregnancy: Case Report.Journal of clinical medicine · 2025
    Article
  5. Temporary uterine artery blocking and uterine artery embolization in treating cesarean scar pregnancy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Roxana BohilteaDiscipline of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu, 020021 Bucharest, Romania.ORCID 0000-0002-6381-7419
Ionita DucuDepartment of Obstetrics and Gynecology, University Emergency Hospital Bucharest, 169 Splaiul Independentei Bld., Sector 5, 050098 Bucharest, Romania.
Bianca MihaiDepartment of Obstetrics and Gynecology, Filantropia Hospital, 11-13 Ion Mihalache Blv., Sector 1, 011171 Bucharest, Romania.ORCID 0000-0002-8957-737X
Ana-Maria IordacheOptospintronics Department, National Institute for Research and Development in Optoelectronics-INOE 2000, 409 Atomistilor, 077125 Magurele, Romania.
Bogdan DorobatDepartment of Interventional Radiology, University Emergency Hospital Bucharest, 169 Splaiul Independentei Bld., Sector 5, 050098 Bucharest, Romania.
Emilia Maria VladareanuFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu, 020021 Bucharest, Romania.
Stefan-Marian IordacheOptospintronics Department, National Institute for Research and Development in Optoelectronics-INOE 2000, 409 Atomistilor, 077125 Magurele, Romania.ORCID 0000-0002-9840-9896
Alexia-Teodora BohilteaÉcole Hôtelière de Lausanne, 1000 Lausanne, Switzerland.
Nicolae BacalbasaDiscipline of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu, 020021 Bucharest, Romania.
Cristiana Eugenia Ana GrigorescuOptospintronics Department, National Institute for Research and Development in Optoelectronics-INOE 2000, 409 Atomistilor, 077125 Magurele, Romania.ORCID 0000-0002-1609-8001
Valentin VarlasDiscipline of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu, 020021 Bucharest, Romania.ORCID 0000-0002-8342-9819
Carol Davila University of Medicine and Pharmacy · RONational Institute of Research and Development for Optoelectronics · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study is to propose a standardized management of care for patients diagnosed with cesarean scar pregnancy (CSP). There are two types of CSP: Type 1 (on the scar) vs. type 2 (in the niche). To date there is no international standard to predict the extent of invasion or the optimal management of CSP. MATERIALS AND

methodsWe used intramuscular methotrexate injection followed by uterine artery embolization combined with suction evacuation as a conservative approach for the treatment of seven patients diagnosed with CSP. Our inclusion criteria, to be satisfied simultaneously, were established as follows: (1) patients with CSP; (2) early gestational age ≤ 9 weeks, and (3) written consent of the proposed treatment of the patient.

resultsThis course of treatment produced a positive outcome in all cases. We did not have any complications (e.g., emergency hysterectomy, perforation of the uterine cavity, severe hemorrhage, or endometritis) during the procedures or in the follow-up. The most important predictors of successful management are early diagnosis of CSP and orientation of the invasive trophoblast opposite to the scar.

conclusionsThe main finding from this series of cases is that associating systemic methotrexate and uterine artery embolization provides efficient and low-risk management of CSP. This treatment regime is adequate for both types of CSPs. We consider that early localization diagnosis of pregnancy following a cesarean delivery is mandatory for CSP morbidity prevention.

Indexed as

cesarean scar pregnancyCSP registryinvasive placentauterine artery embolization

Identifiers

PMID34943587
PMCPMC8700670
OpenAlexW4200252473

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.