Evidence map›Paper›PMID 34943550›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Role of Optical Coherence Tomography Imaging in Predicting Progression of Age-Related Macular Disease: A Survey.

Mohamed Elsharkawy, Mostafa Elrazzaz, Mohammed Ghazal, Marah Alhalabi, Ahmed Soliman, Ali Mahmoud, Eman El-Daydamony, Ahmed Atwan, Aristomenis Thanos, Harpal Singh Sandhu and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Correlation of drusen burden and vascular integrity in age-related macular degeneration using three-dimensional choroidal vascular model.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohamed ElsharkawyBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-9242-9709
Mostafa ElrazzazBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-8842-418X
Mohammed GhazalElectrical and Computer Engineering Department, College of Engineering, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.ORCID 0000-0002-9045-6698
Marah AlhalabiElectrical and Computer Engineering Department, College of Engineering, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.ORCID 0000-0001-8190-5263
Ahmed SolimanBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-1931-3416
Ali MahmoudBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0003-2557-9699
Eman El-DaydamonyFaculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt.
Ahmed AtwanFaculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt.
Aristomenis ThanosLegacy Devers Eye Institute, Portland, OR 97210, USA.
Harpal Singh SandhuBioengineering Department, University of Louisville, Louisville, KY 40292, USA.
Guruprasad GiridharanBioengineering Department, University of Louisville, Louisville, KY 40292, USA.
Ayman El-BazBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-7264-1323

Funding

ASPIRE Award for Research Excellence 2019 under the Advanced Technology Research Council - ASPIRE.
6 · The paper itself

Abstract

In developed countries, age-related macular degeneration (AMD), a retinal disease, is the main cause of vision loss in the elderly. Optical Coherence Tomography (OCT) is currently the gold standard for assessing individuals for initial AMD diagnosis. In this paper, we look at how OCT imaging can be used to diagnose AMD. Our main aim is to examine and compare automated computer-aided diagnostic (CAD) systems for diagnosing and grading of AMD. We provide a brief summary, outlining the main aspects of performance assessment and providing a basis for current research in AMD diagnosis. As a result, the only viable alternative is to prevent AMD and stop both this devastating eye condition and unwanted visual impairment. On the other hand, the grading of AMD is very important in order to detect early AMD and prevent patients from reaching advanced AMD disease. In light of this, we explore the remaining issues with automated systems for AMD detection based on OCT imaging, as well as potential directions for diagnosis and monitoring systems based on OCT imaging and telemedicine applications.

Indexed as

age-related macular degeneration (AMD)computer-aided diagnostic (CAD)dry AMDoptical coherence tomography (OCT)wet AMD

Identifiers

PMID34943550
PMCPMC8699887

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.