Evidence map›Paper›PMID 34943528›Full record

ArticleDiagnostics (Basel, Switzerland)2021

The Reliability of Two- and Three-Dimensional Cephalometric Measurements: A CBCT Study.

Chenshuang Li, Hellen Teixeira, Nipul Tanna, Zhong Zheng, Stephanie Hsiang Yi Chen, Min Zou, Chun-Hsi Chung

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06320665 (Assessment of Vertical Pattern in Correlation With Third Molar Inclusion), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06320665 recruitingnot on this mapstarted 2024, after this paper: background citation

Assessment of Vertical Pattern in Correlation With Third Molar Inclusion : a 3D CBCT Analysis

TypeobservationalSponsorCentral Hospital, Nancy, FranceRan2024 to 2025Enrolled80ConditionsImpacted Third Molar ToothArmsRadiographic measurement
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Are the results of the Wits appraisal clinically interchangeable when evaluating 2D and 3D images? : A CBCT-dataset method-comparison study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
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  18. An Update on Advanced Diagnostic Imaging in Dentistry.Diagnostics (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenshuang LiDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-6331-6983
Hellen TeixeiraDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Nipul TannaDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Zhong ZhengDavid Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0002-4905-3563
Stephanie Hsiang Yi ChenDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Min ZouKey Laboratory of Shannxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, 98 XiWu Road, Xi'an 710004, China.
Chun-Hsi ChungDepartment of Orthodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Funding

American Association of Orthodontists Full-Time Faculty Fellowship AwardAmerican Association of Orthodontists Foundation Orthodontic Faculty Development Fellowship Awardthe Department of Orthodontics, University of Pennsylvania School of Dental Medicine the J. Henry O'Hern Jr. Pilot GrantUniversity of Pennsylvania School of Dental Medicine Joseph and Josephine Rabinowitz Award for Excellence in Research
6 · The paper itself

Abstract

Cephalometry is a standard diagnostic tool in orthodontic and orthognathic surgery fields. However, built-in magnification from the cephalometric machine produces double images from left- and right-side craniofacial structures on the film, which poses difficulty for accurate cephalometric tracing and measurements. The cone-beam computed tomography (CBCT) images not only allow three-dimensional (3D) analysis, but also enable the extraction of two-dimensional (2D) images without magnification. To evaluate the most reliable cephalometric analysis method, we extracted 2D lateral cephalometric images with and without magnification from twenty full-cranium CBCT datasets; images were extracted with magnification to mimic traditional lateral cephalograms. Cephalometric tracings were performed on the two types of extracted 2D lateral cephalograms and on the reconstructed 3D full cranium images by two examiners. The intra- and inter-examiner intraclass correlation coefficients (ICC) were compared between linear and angular parameters, as well as between CBCT datasets of adults and children. Our results showed that overall, tracing on 2D cephalometric images without magnification increased intra- and inter-examiner reliability, while 3D tracing reduced inter-examiner reliability. Angular parameters and children's images had the lowest inter- and intra-examiner ICCs compared with adult samples and linear parameters. In summary, using lateral cephalograms extracted from CBCT without magnification for tracing/analysis increased reliability. Special attention is needed when analyzing young patients' images and measuring angular parameters.

Indexed as

CBCTcephalometric analysisorthodonticsthree-dimensionaltwo-dimensional

Identifiers

PMID34943528
PMCPMC8700671

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.