Evidence map›Paper›PMID 34943527›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Estimating Glomerular Filtration Rate from Serum Myo-Inositol, Valine, Creatinine and Cystatin C.

Frank Stämmler, Marcello Grassi, Jeffrey W Meeusen, John C Lieske, Surendra Dasari, Laurence Dubourg, Sandrine Lemoine, Jochen Ehrich, Eric Schiffer

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  9. Analytical Validation of GFRDiagnostics (Basel, Switzerland) · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Frank StämmlerDepartment of Research and Development, numares AG, 93053 Regensburg, Germany.ORCID 0000-0003-2841-0610
Marcello GrassiDepartment of Research and Development, numares AG, 93053 Regensburg, Germany.
Jeffrey W MeeusenDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
John C LieskeDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-0202-5944
Surendra DasariDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN 55905, USA.
Laurence DubourgService d'Explorations Fonctionnelles Rénales et Métaboliques, Hôpital Edouard Herriot, 69437 Lyon, France.
Sandrine LemoineService d'Explorations Fonctionnelles Rénales et Métaboliques, Hôpital Edouard Herriot, 69437 Lyon, France.
Jochen EhrichChildren's Hospital, Hannover Medical School, 30625 Hannover, Germany.
Eric SchifferDepartment of Research and Development, numares AG, 93053 Regensburg, Germany.
Hôpital Edouard Herriot · FRMayo Clinic · USMayo Clinic in Arizona · USMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assessment of renal function relies on the estimation of the glomerular filtration rate (eGFR). Existing eGFR equations, usually based on serum levels of creatinine and/or cystatin C, are not uniformly accurate across patient populations. In the present study, we expanded a recent proof-of-concept approach to optimize an eGFR equation targeting the adult population with and without chronic kidney disease (CKD), based on a nuclear magnetic resonance spectroscopy (NMR) derived 'metabolite constellation' (GFR

Indexed as

chronic kidney diseaseCKDcystatin CeGFReGFR equationfiltration markersglomerular filtration ratemetaboliteNMRserum creatinine

Identifiers

PMID34943527
PMCPMC8700166
OpenAlexW4200595744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.