Evidence map›Paper›PMID 34943506›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Supplementation of Probiotic

Yen-Chieh Wang, Wei-Chi Ku, Chih-Yi Liu, Yu-Che Cheng, Chih-Cheng Chien, Kang-Wei Chang, Chi-Jung Huang

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  4. The emerging role of the microbiome in bladder cancer: prognostic implications and treatment response.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yen-Chieh WangDepartment of Urology, Cathay General Hospital, Taipei 106438, Taiwan.
Wei-Chi KuSchool of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242062, Taiwan.ORCID 0000-0001-8438-3210
Chih-Yi LiuSchool of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242062, Taiwan.ORCID 0000-0002-3996-8452
Yu-Che ChengSchool of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242062, Taiwan.
Chih-Cheng ChienSchool of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242062, Taiwan.
Kang-Wei ChangTaipei Neuroscience Institute, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0002-4476-3603
Chi-Jung HuangDepartment of Medical Research, Cathay General Hospital, Taipei 106438, Taiwan.
Fu Jen Catholic University · TWCathay General Hospital · TWTaipei Medical University · TW

Funding

Cathay General Hospital CGH-2020
6 · The paper itself

Abstract

In bladder cancer, urothelial carcinoma is the most common histologic subtype, accounting for more than 90% of cases. Pathogenic effects due to the dysbiosis of gut microbiota are localized not only in the colon, but also in regulating bladder cancer distally. Butyrate, a short-chain fatty acid produced by gut microbial metabolism, is mainly studied in colon diseases. Therefore, the resolution of the anti-cancer effects of butyrate-producing microbes on bladder urothelial cells and knowledge of the butyrate-responsive molecules must have clinical significance. Here, we demonstrate a correlation between urothelial cancer of the bladder and

Indexed as

apoptosisbladder cancer-associated proteinbutyrateButyricicoccus pullicaecorumurothelial bladder cancer

Identifiers

PMID34943506
PMCPMC8700285
OpenAlexW4200062292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.