Evidence map›Paper›PMID 34943447›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Validation of a Monte Carlo Modelling Based Dosimetry of Extraoral Photobiomodulation.

Anna N Yaroslavsky, Amy F Juliano, Ather Adnan, Wayne J Selting, Tyler W Iorizzo, James D Carroll, Stephen T Sonis, Christine N Duncan, Wendy B London, Nathaniel S Treister

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Anna N YaroslavskyAdvanced Biophotonics Laboratory, Department of Physics and Applied Physics, University of Massachusetts Lowell, Lowell, MA 01854, USA.ORCID 0000-0001-7914-2324
Amy F JulianoDepartment of Radiology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
Ather AdnanTexas A&M Health Science Center, College of Medicine, Houston, TX 77030, USA.
Wayne J SeltingDepartment of Surgical Science and Integrated Diagnostics, University of Genoa, 16123 Genoa, Italy.
Tyler W IorizzoAdvanced Biophotonics Laboratory, Department of Physics and Applied Physics, University of Massachusetts Lowell, Lowell, MA 01854, USA.ORCID 0000-0001-9046-9299
James D CarrollTHOR Photomedicine, Chesham HP5 1LF, UK.
Stephen T SonisDepartment of Surgery, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA 02114, USA.ORCID 0000-0001-6480-2625
Christine N DuncanDepartment of Pediatrics, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA 02114, USA.
Wendy B LondonDepartment of Pediatrics, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA 02114, USA.
Nathaniel S TreisterDepartment of Surgery, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA 02114, USA.ORCID 0000-0002-5596-7222
Brigham and Women's Hospital · USHarvard University · USUniversity of Massachusetts Lowell · USMassachusetts Eye and Ear Infirmary · USTexas A&M Health Science Center · USUniversity of Genoa · IT

Funding

Extraorally delivered lo level light therapy for prevention of oropharyngeal mucositis in pediatric patients undergoing hematopoietic stem cell transplantationR34DE025908 · NIDCR · BRIGHAM AND WOMEN'S HOSPITAL · PI DUNCAN, CHRISTINE NOEL, TREISTER, NATHANIEL S · 2016 to 2016
$322k
NIDCR NIH HHS 1R34DE025908
6 · The paper itself

Abstract

An in vivo validation study was performed to confirm the accuracy of extraoral photobiomodulation therapy (PBMT) dosimetry determined by modelling. The Monte Carlo technique was utilized to calculate the fluence rate and absorbed power of light delivered through multi-layered tissue. Optical properties used during Monte Carlo simulations were taken from the literature. Morphological data of four study volunteers were acquired using magnetic resonance imaging (MRI) scans. Light emitting diode (LED) coupled to a power meter were utilized to measure transmitted power through each volunteer's cheek, in vivo. The transmitted power determined by Monte Carlo modelling was compared to the in vivo measurements to determine the accuracy of the simulations. Experimental and simulation results were in good agreement for all four subjects. The difference between the mean values of the measured transmission was within 12% from the respective transmission obtained using Monte Carlo simulations. The results of the study indicate that Monte Carlo modelling is a robust and reliable method for light dosimetry.

Indexed as

in vivo dosimetrylow-level light therapyMonte Carlo methodmucositis

Identifiers

PMID34943447
PMCPMC8700113
OpenAlexW3217323622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.