Evidence map›Paper›PMID 34943441›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Impact of Epiretinal Membrane on Optical Coherence Tomography Tools Used for Monitoring Glaucoma.

Marco Rocco Pastore, Riccardo Merli, Carmen Dell'Aquila, Lorenzo Belfanti, Marco Franzon, Gabriella Cirigliano, Chiara De Giacinto, Rosa Giglio, Daniele Tognetto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Premacular membranes and glaucoma: a review of clinical and therapeutic considerations.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Marco Rocco PastoreEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.ORCID 0000-0002-4725-1590
Riccardo MerliEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.
Carmen Dell'AquilaEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.
Lorenzo BelfantiEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.
Marco FranzonDepartment of Mathematics and Computer Science, University of Trieste, 34129 Trieste, Italy.ORCID 0000-0001-6237-7039
Gabriella CiriglianoEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.
Chiara De GiacintoEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.
Rosa GiglioEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.ORCID 0000-0001-9755-0786
Daniele TognettoEye Clinic, Department of Medical, Surgical Sciences and Health, University of Trieste, 34129 Trieste, Italy.
University of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) measurements can be influenced by many factors including the presence of concomitant retinal diseases. The aim of this study it to assess the impact of epiretinal membrane (ERM) on RNFL and GCL assessment using optical coherence tomography (OCT).

methodsGCL, peripapillary RNFL (pRNFL), and Bruch's Membrane Opening Minimum Rim Width (BMO-MRW) thicknesses were analysed using an SD-OCT (Spectralis OCT) in eyes with idiopathic ERM and compared with a control group.

results161 eyes were included, 73 eyes in the control group and 88 eyes with idiopathic ERM. The pRNFL analysis revealed a statistically significant difference between the two groups in overall and temporal sector thicknesses. For GCL thickness report, the percentage of scans in which the GCL was erroneously segmented by automatic segmentation was assessed for each eye. A statistically significant difference was found in all sectors (

conclusionIn eyes with ERM, the GCL and pRNFL analysis seemed affected by the morphological retinal layers' modification. MRW-BMO did not appear to be directly affected by the presence of ERM.

Indexed as

Bruch’s Membrane Opening Minimum Rim Widthepiretinal membrane (ERM)ganglion cell layer (GCL)glaucomaoptical coherence tomography (OCT)peripapillary retinal nerve fiber layer (pRNFL)

Identifiers

PMID34943441
PMCPMC8700323
OpenAlexW3215085583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.