ArticleDiagnostics (Basel, Switzerland)2021
Dose Reduction in Coronary Artery Calcium Scoring Using Mono-Energetic Images from Reduced Tube Voltage Dual-Source Photon-Counting CT Data: A Dynamic Phantom Study.
Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Photon-counting CT versus energy-integrating detectors for cardiac imaging: a systematic review of evidence from in vivo human studies on image quality and radiation dose.BMC medical imaging · 2025Pooled it
- Spectral Imaging Techniques in Heart Disease Assessment Using Photon-Counting Detector Computed Tomography.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Quantification accuracy in photon-counting detector CT for coronary artery calcium score: a pilot study.The international journal of cardiovascular imaging · 2024Article
- Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Intraindividual Comparison of Dose Reduction and Coronary Calcium Scoring Accuracy Using Kilovolt-independent and Tin Filtration CT Protocols.Radiology. Cardiothoracic imaging · 2024Article
- Spectral Photon-Counting Computed Tomography: Technical Principles and Applications in the Assessment of Cardiovascular Diseases.Journal of clinical medicine · 2024Review
- Virtual non-iodine photon-counting CT-angiography for aortic valve calcification scoring.Scientific reports · 2024Article
- Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.Radiology · 2023Review
- Cardiovascular Applications of Photon-Counting CT Technology: A Revolutionary New Diagnostic Step.Journal of cardiovascular development and disease · 2023Review
- Article
- Dual-Source Photon-Counting Computed Tomography-Part I: Clinical Overview of Cardiac CT and Coronary CT Angiography Applications.Journal of clinical medicine · 2023Review
- Radiation Dose Reduction for Coronary Artery Calcium Scoring Using a Virtual Noniodine Algorithm on Photon-Counting Detector Computed-Tomography Phantom Data.Diagnostics (Basel, Switzerland) · 2023Article
- An introduction to photon-counting detector CT (PCD CT) for radiologists.Japanese journal of radiology · 2023Review
- Phantom-based quantification of the spectral accuracy in dual-layer spectral CT for pediatric imaging at 100 kVp.Quantitative imaging in medicine and surgery · 2023Article
- First-generation clinical dual-source photon-counting CT: ultra-low-dose quantitative spectral imaging.European radiology · 2022Article
- Reproducibility of coronary artery calcium quantification on dual-source CT and dual-source photon-counting CT: a dynamic phantom study.The international journal of cardiovascular imaging · 2022Article
- Dual-source photon-counting CT: consistency in spectral results at different acquisition modes and heart rates.Proceedings of SPIE--the International Society for Optical Engineering · 2022Article
- Quantum Iterative Reconstruction for Low-Dose Ultra-High-Resolution Photon-Counting Detector CT of the Lung.Diagnostics (Basel, Switzerland) · 2022Article
- Intra-individual comparison of coronary calcium scoring between photon counting detector- and energy integrating detector-CT: Effects on risk reclassification.Frontiers in cardiovascular medicine · 2022Article
- Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer.Diagnostics (Basel, Switzerland) · 2021Article
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8 authors.
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Abstract
In order to assess coronary artery calcium (CAC) quantification reproducibility for photon-counting computed tomography (PCCT) at reduced tube potential, an anthropomorphic thorax phantom with low-, medium-, and high-density CAC inserts was scanned with PCCT (NAEOTOM Alpha, Siemens Healthineers) at two heart rates: 0 and 60-75 beats per minute (bpm). Five imaging protocols were used: 120 kVp standard dose (IQ level 16, reference), 90 kVp at standard (IQ level 16), 75% and 45% dose and tin-filtered 100 kVp at standard dose (IQ level 16). Each scan was repeated five times. Images were reconstructed using monoE reconstruction at 70 keV. For each heart rate, CAC values, quantified as Agatston scores, were compared with the reference, whereby deviations >10% were deemed clinically relevant. Reference protocol radiation dose (as volumetric CT dose index) was 4.06 mGy. Radiation dose was reduced by 27%, 44%, 67%, and 46% for the 90 kVp standard dose, 90 kVp 75% dose, 90 kVp 45% dose, and Sn100 standard dose protocol, respectively. For the low-density CAC, all reduced tube current protocols resulted in clinically relevant differences with the reference. For the medium- and high-density CAC, the implemented 90 kVp protocols and heart rates revealed no clinically relevant differences in Agatston score based on 95% confidence intervals. In conclusion, PCCT allows for reproducible Agatston scores at a reduced tube voltage of 90 kVp with radiation dose reductions up to 67% for medium- and high-density CAC.
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