Evidence map›Paper›PMID 34943427›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Visualization of Complex Processes in Cardiovascular System during Electrical Auricular Vagus Nerve Stimulation.

Vaiva Šiaučiūnaitė, Minvydas Ragulskis, Alfonsas Vainoras, Babak Dabiri, Eugenijus Kaniusas

Abstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vaiva ŠiaučiūnaitėDepartment of Mathematical Modelling, Kaunas University of Technology, 51368 Kaunas, Lithuania.ORCID 0000-0003-2753-6035
Minvydas RagulskisDepartment of Mathematical Modelling, Kaunas University of Technology, 51368 Kaunas, Lithuania.ORCID 0000-0002-3348-9717
Alfonsas VainorasCardiology Institute, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.ORCID 0000-0002-5732-8520
Babak DabiriInstitute of Electrodynamics, Microwave and Circuit Engineering, Vienna University of Technology, 1040 Vienna, Austria.
Eugenijus KaniusasInstitute of Electrodynamics, Microwave and Circuit Engineering, Vienna University of Technology, 1040 Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analysis of human physiological systems from the point of view of complex systems theory remains a very ambitious task. The complexity of the problem often encourages the use of innovative mathematical methods analyzing the processes that take place in space and time. The main goal of this paper is to visualize the cardiovascular system during auricular vagus nerve stimulation (aVNS) using the matrix differences to evaluate the dynamic signal interfaces by cointegrating the initial signal data into the matrices during each case. Algebraic relationships between RR/JT and JT/QRS cardiac intervals are used not only to track the cardiovascular changes during aVNS but also to characterize individual features of the person during the transit through the therapy. This paper presents the computational techniques that can visualize the complex dynamical processes taking place in the cardiovascular system using the electrical aVNS therapy. Four healthy volunteers participated in two verum and two placebo experiments. We discovered that the body's reaction to the stimulation was very different in each of the cases, but the presented techniques opened new possibilities for a novel interpretation of the dynamics of the cardiovascular system.

Indexed as

auricular vagus nerve stimulationcardiac intervalselectrocardiography

Identifiers

PMID34943427
PMCPMC8700405

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.