Evidence map›Paper›PMID 34943425›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Application and Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio in Patients with Ischemic and Non-Ischemic Cardiomyopathy.

Stanislav Keranov, Saskia Haen, Julia Vietheer, Wiebke Rutsatz, Jan-Sebastian Wolter, Steffen D Kriechbaum, Beatrice von Jeinsen, Pascal Bauer, Khodr Tello, Manuel Richter and 7 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The tricuspid annular plane systolic excursion/PASP ratio's accuracy and validity in assessing the right ventricular function: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Stanislav KeranovDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-4379-4424
Saskia HaenDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Julia VietheerKerckhoff Heart and Thorax Center, Department of Cardiology, 61231 Bad Nauheim, Germany.
Wiebke RutsatzDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Jan-Sebastian WolterKerckhoff Heart and Thorax Center, Department of Cardiology, 61231 Bad Nauheim, Germany.
Steffen D KriechbaumDZHK (German Center for Cardiovascular Research), Partner Site RheinMain, 61231 Bad Nauheim, Germany.
Beatrice von JeinsenKerckhoff Heart and Thorax Center, Department of Cardiology, 61231 Bad Nauheim, Germany.
Pascal BauerDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-6036-8689
Khodr TelloDepartment of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), 35392 Giessen, Germany.
Manuel RichterDepartment of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), 35392 Giessen, Germany.
Oliver DörrDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.ORCID 0000-0003-4526-6956
Andreas J RiethKerckhoff Heart and Thorax Center, Department of Cardiology, 61231 Bad Nauheim, Germany.
Holger NefDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Christian W HammDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Christoph LiebetrauDZHK (German Center for Cardiovascular Research), Partner Site RheinMain, 61231 Bad Nauheim, Germany.
Andreas RolfKerckhoff Heart and Thorax Center, Department of Cardiology, 61231 Bad Nauheim, Germany.
Till KellerDepartment of Internal Medicine I, Cardiology and Angiology, Justus-Liebig-University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-0895-6491
Justus-Liebig-Universität Gießen · DEKerckhoff Klinik · DECardiovascular Center Bethanien · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of this study was to assess the prognostic utility of TAPSE/PASP as an echocardiographic parameter of maladaptive RV remodeling in cardiomyopathy patients using cardiac magnetic resonance (CMR) imaging. Furthermore, we sought to compare TAPSE/PASP to TAPSE. The association of the echocardiographic parameters TAPSE/PASP and TAPSE with CMR parameters of RV and LV remodeling was evaluated in 111 patients with ischemic and non-ischemic cardiomyopathy and cut-off values for maladaptive RV remodeling were defined. In a second step, the prognostic value of TAPSE/PASP and its cut-off value were analyzed regarding mortality in a validation cohort consisting of 221 patients with ischemic and non-ischemic cardiomyopathy. A low TAPSE/PASP (<0.38 mm/mmHg) and TAPSE (<16 mm) were associated with a lower RVEF and a long-axis RV global longitudinal strain (GLS) as well as higher RVESVI, RVEDVI and NT-proBNP. A low TAPSE/PASP, but not TAPSE, was associated with a lower LVEF and long-axis LV GLS, and a higher LVESVI, LVEDVI and T1 relaxation time at the interventricular septum and the RV insertion points. Furthermore, in the validation cohort, low TAPSE/PASP was associated with a higher mortality and TAPSE/PASP was an independent predictor of mortality. TAPSE/PASP is a predictor of maladaptive RV and LV remodeling associated with poor outcomes in cardiomyopathy patients.

Indexed as

LV remodelingMRIRVEFRV remodelingT1 mappingTAPSE/PASP

Identifiers

PMID34943425
PMCPMC8700391
OpenAlexW3214858578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.