Evidence map›Paper›PMID 34943387›Full record

ArticleChildren (Basel, Switzerland)2021

Human Microbiome in Children, at the Crossroad of Social Determinants of Health and Personalized Medicine.

Talía Sainz, Valeria Pignataro, Donato Bonifazi, Simona Ravera, María José Mellado, Antonio Pérez-Martínez, Adela Escudero, Adriana Ceci, Cristina Calvo

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Talía SainzHospital La Paz, Pº Castellana 261, 28046 Madrid, Spain.ORCID 0000-0002-5301-0945
Valeria PignataroConsorzio per Valutazioni Biologiche e Farmacologiche, Via N. Putignani n. 178, 70122 Bari, Italy.
Donato BonifaziConsorzio per Valutazioni Biologiche e Farmacologiche, Via N. Putignani n. 178, 70122 Bari, Italy.ORCID 0000-0003-2636-9159
Simona RaveraPHArmaceutical Research Management SRL, Via Albert Einstein, 26900 Lodi, Italy.
María José MelladoHospital La Paz, Pº Castellana 261, 28046 Madrid, Spain.ORCID 0000-0003-2251-9666
Antonio Pérez-MartínezHospital La Paz, Pº Castellana 261, 28046 Madrid, Spain.ORCID 0000-0002-6436-9195
Adela EscuderoHospital La Paz, Pº Castellana 261, 28046 Madrid, Spain.ORCID 0000-0001-8101-4014
Adriana CeciConsorzio per Valutazioni Biologiche e Farmacologiche, Via N. Putignani n. 178, 70122 Bari, Italy.
Cristina CalvoHospital La Paz, Pº Castellana 261, 28046 Madrid, Spain.ORCID 0000-0002-6503-3423
Hospital Universitario La Paz · ESConsorzio per Valutazioni Biologiche e Farmacologiche · ITPHARM (Italy) · IT

Funding

European Union- Horizon 2020 777554
6 · The paper itself

Abstract

The evolving field of microbiome research offers an excellent opportunity for biomarker identification, understanding drug metabolization disparities, and improving personalized medicine. However, the complexities of host-microbe ecological interactions hinder clinical transferability. Among other factors, the microbiome is deeply influenced by age and social determinants of health, including environmental factors such as diet and lifestyle conditions. In this article, the bidirectionality of social and host-microorganism interactions in health will be discussed. While the field of microbiome-related personalized medicine evolves, it is clear that social determinants of health should be mitigated. Furthermore, microbiome research exemplifies the need for specific pediatric investigation plans to improve children's health.

Indexed as

childhuman microbiomepersonalized medicinesocial determinants of health

Identifiers

PMID34943387
PMCPMC8700538
OpenAlexW4200544166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.