ReviewChildren (Basel, Switzerland)2021
Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides.
Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Parental and childhood exposures and the risk of retinoblastoma, hepatoblastoma, and germ cell, bone, and soft tissue tumors in children: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Risk factors for childhood brain tumours: A systematic review and meta-analysis of observational studies from 1976 to 2022.Cancer epidemiology · 2024Pooled it
- Integrated Experimental and In-Silico Analysis Indicates Melittin as a Modulator of IL-37a-Associated Networks in Neuroblastoma.The protein journal · 2026Article
- Spatial analysis of residential location at birth, PFAS in public water, and childhood cancers in Southern California (2000-2019).Journal of exposure science & environmental epidemiology · 2026Article
- Formulation Matters: Differential Genotoxic and Cytotoxic Effects of Lambda-Cyhalothrin Pesticide Formulations on Human Hepatocellular Cells.Journal of xenobiotics · 2026Article
- Prenatal pesticide exposure and neuroblastoma - A statewide case-control study in California.Environmental research · 2025Article
- Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats.Environmental health : a global access science source · 2025Article
- A Call for Pediatric Clinicians to Address Environmental Health Concerns in Rural Settings.Pediatric clinics of North America · 2025Review
- Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade.International journal of molecular sciences · 2024Article
- Assessment of rehabilitation treatment for patients with acute poisoning-induced toxic encephalopathy.World journal of emergency medicine · 2024Article
- Review
- Pediatric Hepatic Angiosarcoma (PHAS) and Vinyl Chloride-A Ghost of the Past May Loom over East Palestine, OH, and beyond: A Critical Commentary.Diagnostics (Basel, Switzerland) · 2023Article
- Exposures to pesticides and risk of cancer: Evaluation of recent epidemiological evidence in humans and paths forward.International journal of cancer · 2023Article
- Surface Plasmon Resonance Imaging Sensor for Detection of Photolytically and Photocatalytically Degraded Glyphosate.Sensors (Basel, Switzerland) · 2022Article
- Recent Progress in Nanotechnology-Based Approaches for Food Monitoring.Nanomaterials (Basel, Switzerland) · 2022Review
- Translational pediatrics: reflections for the 21Translational pediatrics · 2022Article
- Influence of pesticide exposure on farmers' cognition: A systematic review.Journal of neurosciences in rural practiceReview
- Pesticides and human health.Jornal de pediatriaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 4 countries.
Funding
Abstract
backgroundBrain tumors are the second most common neoplasm in the pediatric age. Pesticides may play an etiologic role, but literature results are conflicting. This review provides a systematic overview, meta-analysis, and IARC/WHO consideration of data on parental exposure to pesticides and childhood brain tumors.
methodsWe searched PubMed, SCOPUS, and Google Scholar for literature (1 January 1966-31 December 2020) that assessed childhood brain tumors and parental exposure to pesticides. We undertook a meta-analysis addressing prenatal exposure, exposure after birth, occupational exposure, and residential exposure. A total of 130 case-control investigations involving 43,598 individuals (18,198 cases and 25,400 controls) were included.
resultsPrenatal exposure is associated with childhood brain tumors (odds ratio, OR = 1.32; 95% CI: 1.17-1.49; I
conclusionsThere is an association between CBT and parental pesticides exposure before childbirth, after birth, and residential exposure. It is in line with the IARC Monograph evaluating the carcinogenicity of diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.