Evidence map›Paper›PMID 34943259›Full record

ArticleBiology2021

Production of d-Tagatose by Whole-Cell Conversion of Recombinant

Xian Zhang, Ruiqi Lu, Qiang Wang, Mengkai Hu, Zhiyue Li, Meijuan Xu, Taowei Yang, Rongzhen Zhang, Zhiming Rao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Engineering the L-Arabinose Isomerase fromMolecules (Basel, Switzerland) · 2026
    Article
  3. Engineering ofCurrent research in food science · 2026
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xian ZhangThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Ruiqi LuThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Qiang WangThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Mengkai HuThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Zhiyue LiThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Meijuan XuThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Taowei YangThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Rongzhen ZhangThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
Zhiming RaoThe Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.ORCID 0000-0003-2495-0660
Jiangnan University · CN

Funding

111 Project 111-2-06Key Research and Development Program of Ningxia Hui Autonomous Region 2020BFH02011Key Research and Development Project of Shandong Province, China 2019JZZY020605National Natural Science Foundation of China 32171471Program of the Key Laboratory of Industrial Biotechnology, Ministry of Education, China KLIB-KF202103the National Key Research and Development Program of China 2021YFC2100900
6 · The paper itself

Abstract

d-tagatose is a popular functional monosaccharide produced from lactose by β-galactosidase and arabinose isomerase. In this study, two d-alanine-deficient heterologous gene expression systems were constructed,

Indexed as

arabinose isomeraseBacillus subtilisd-alanine racemased-tagatosefood-gradewhole-cell bioconversionβ-galactosidase

Identifiers

PMID34943259
PMCPMC8698901
OpenAlexW4200533175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.