Evidence map›Paper›PMID 34943185›Full record

ArticleBiology2021

Evaluation of Global DNA Methylation and Gene Expression of

Akifumi Nakata, Keisuke Sato, Yohei Fujishima, Valerie Goh Swee Ting, Kanade Nakayama, Kentaro Ariyoshi, Chizuru Tsuruoka, Yi Shang, Daisuke Iizuka, Shizuko Kakinuma and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Akifumi NakataFaculty of Pharmaceutical Sciences, Hokkaido University of Science, Sapporo 006-8585, Japan.ORCID 0000-0002-8728-1655
Keisuke SatoFaculty of Pharmaceutical Sciences, Hokkaido University of Science, Sapporo 006-8585, Japan.
Yohei FujishimaDepartment of Risk Analysis and Biodosimetry, Institute of Radiation Emergency Medicine, Hirosaki University, Hirosaki 036-8564, Japan.
Valerie Goh Swee TingDepartment of Radiobiology, Singapore Nuclear Research and Safety Initiative, National University of Singapore, Singapore 138602, Singapore.ORCID 0000-0002-0016-609X
Kanade NakayamaFaculty of Pharmaceutical Sciences, Hokkaido University of Science, Sapporo 006-8585, Japan.
Kentaro AriyoshiCenter for Integrated Science and Humanities, Fukushima Medical University, Fukushima 960-1247, Japan.ORCID 0000-0002-4639-6130
Chizuru TsuruokaDepartment of Radiation Effects Research, National Institute of Radiological Sciences (NIRS), National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Yi ShangDepartment of Radiation Effects Research, National Institute of Radiological Sciences (NIRS), National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Daisuke IizukaDepartment of Radiation Effects Research, National Institute of Radiological Sciences (NIRS), National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Shizuko KakinumaDepartment of Radiation Effects Research, National Institute of Radiological Sciences (NIRS), National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Hideaki YamashiroGraduate School of Science and Technology, Niigata University, Niigata 959-2181, Japan.
Tomisato MiuraDepartment of Risk Analysis and Biodosimetry, Institute of Radiation Emergency Medicine, Hirosaki University, Hirosaki 036-8564, Japan.ORCID 0000-0003-3104-2134
National Institutes for Quantum Science and Technology · JPHirosaki University · JPHokkaido University of Science · JPFukushima Medical University · JPNiigata University · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology 17S17942991
6 · The paper itself

Abstract

The intergenerational effects from chronic low-dose exposure are matters of concern. It is thus important to elucidate the radiation-induced effects of germ cell maturation, fertilization and embryonic development. It is well known that DNA methylation levels in CpG sites in gametes are reprogrammed in stages during their maturity. Furthermore, the binding of

Indexed as

dose-rate effectglobal DNA methylationirradiation before sexual maturityIzumo1Izumo1rovarytestis

Identifiers

PMID34943185
PMCPMC8698457
OpenAlexW4200420243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.