Evidence map›Paper›PMID 34943129›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Dried Blood Spot Biomarkers of Oxidative Stress and Inflammation Associated with Blood Pressure in Rural Senegalese Women with Incident Hypertension.

Yan Lin, Xiangtian Wang, Luciane Lenz, Ousmane Ndiaye, Jian Qin, Xiaoli Wang, Hui Huang, Marc A Jeuland, Junfeng Zhang

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Dried Blood Spots to Assess Cardiovascular-Kidney-Metabolic Health.Journal of the American Heart Association · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Biomarkers of Oxidative Stress in Acute and Chronic Diseases.Antioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Yan LinNicholas School of the Environment & Duke Global Health Institute, Duke University, Durham, NC 27705, USA.ORCID 0000-0003-4384-8354
Xiangtian WangNicholas School of the Environment & Duke Global Health Institute, Duke University, Durham, NC 27705, USA.ORCID 0000-0001-5957-2626
Luciane LenzRWI Leibniz Institute for Economic Research, 10115 Berlin, Germany.
Ousmane NdiayeCentre de Recherche pour le Développement Economique et Social (CRDES), Université Gaston-Berger, Saint-Louis, P.O. Box 234, Senegal.
Jian QinNicholas School of the Environment & Duke Global Health Institute, Duke University, Durham, NC 27705, USA.
Xiaoli WangNicholas School of the Environment & Duke Global Health Institute, Duke University, Durham, NC 27705, USA.
Hui HuangNicholas School of the Environment & Duke Global Health Institute, Duke University, Durham, NC 27705, USA.
Marc A JeulandRWI Leibniz Institute for Economic Research, 10115 Berlin, Germany.ORCID 0000-0001-8325-2622
Junfeng ZhangNicholas School of the Environment & Duke Global Health Institute, Duke University, Durham, NC 27705, USA.ORCID 0000-0003-3759-6672
Duke University · USRWI – Leibniz Institute for Economic Research · DETianjin University of Technology · CNGuangxi Medical University · CNUniversité Gaston Berger · SN

Funding

Duke University's Energy Initiative N/AGerman Corporation for International Cooperation GmbH N/AGerman Federal Ministry of Education and Research N/AInternational Initiative for Impact Evaluation (3ie) N/A
6 · The paper itself

Abstract

Blood biomarkers of oxidative stress and inflammation have been associated with increased risk of hypertension development; yet their application in sub-Saharan Africa has been limited due to the lack of blood collection facilities. In this study, we evaluated the usefulness of dried blood spots (DBS), a more feasible alternative to venous blood, in rural sub-Saharan residents. We recruited 342 women with incident hypertension from rural Senegal, and measured C-reactive protein (CRP) and malondialdehyde (MDA) in DBS and concurrent blood pressure (BP) at baseline and 1-year follow-up. Associations of DBS biomarkers with current levels of and 1-year changes in BP were examined after adjusting for demographic, medical, and socioeconomic covariates. DBS concentrations of MDA were significantly associated with concurrent systolic BP (SBP) (

Indexed as

biomarkerblood pressurec-reactive proteindried blood spothypertensionmalondialdehyde

Identifiers

PMID34943129
PMCPMC8698702
OpenAlexW4200615684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.