Evidence map›Paper›PMID 34943111›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Non-Invasive Measurement of Exercise-Induced Oxidative Stress in Response to Physical Activity. A Systematic Review and Meta-Analysis.

Giulia Squillacioti, Fulvia Guglieri, Nicoletta Colombi, Federica Ghelli, Paola Berchialla, Paolo Gardois, Roberto Bono

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Physical Activity and Arterial Stiffness: A Narrative Review.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Review
  5. Oxidative Stress in Pregnancy.Biomolecules · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giulia SquillaciotiDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-0655-7550
Fulvia GuglieriDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.
Nicoletta ColombiBiblioteca Federata di Medicina Ferdinando Rossi, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-6870-5590
Federica GhelliDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-2605-3293
Paola BerchiallaDipartimento di Scienze Cliniche e Biologiche, University of Turin, 10043 Turin, Italy.ORCID 0000-0001-5835-5638
Paolo GardoisBiblioteca Federata di Medicina Ferdinando Rossi, University of Turin, 10126 Turin, Italy.
Roberto BonoDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-2471-6594
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity may benefit health by modulating oxidative stress and inflammation. However, the selection of suitable exercise-induced oxidative stress biomarkers is still challenging. This study aimed at systematically summarizing the available evidence on exercise-induced oxidative stress measured in urine and/or saliva. Two meta-analyses including the most frequently quantified biomarkers of oxidative stress, namely, urinary isoprostane and DNA oxidation products, were performed. Three electronic databases (PubMed, EMBASE and Cochrane CENTRAL) were interrogated. Among 4479 records, 43 original articles were included in the systematic review and 11 articles were included in meta-analysis I and II, respectively. We observed a pooled trend of increase of urinary isoprostanes in response to physical activity (+0.95, 95% CI: -0.18; 2.09). In comparison with aerobic exercise, anaerobic training determined a greater induction of isoprostanes (+5.21, 95% CI: 2.76; 7.66,

Indexed as

non-invasive biomarkeroxidative stressphysical activitypublic healthsalivaurine

Identifiers

PMID34943111
PMCPMC8698343
OpenAlexW4200546148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.